Antihypertensive Drugs and Risk of Cancer: Between Scylla and Charybdis-Reference-Cited by-同舟云学术

Antihypertensive Drugs and Risk of Cancer: Between Scylla and Charybdis

Published:2020-06-12 Issue:12 Volume:33 Page:1049-1058
ISSN:0895-7061
Container-title:American Journal of Hypertension
language:en
Short-container-title:

Author:

Sanidas Elias¹,Velliou Maria¹,Papadopoulos Dimitrios¹,Fotsali Anastasia¹,Iliopoulos Dimitrios²,Mantzourani Marina³,Toutouzas Konstantinos⁴,Barbetseas John¹

Affiliation:

1. Hypertension Excellence Centre—ESH, Department of Cardiology, LAIKO General Hospital, Athens, Greece

2. Laboratory of Experimental Surgery and Surgical Research “N.S. Christeas”, University of Athens, Medical School, Athens, Greece

3. 1st Department of Internal Medicine, LAIKO General Hospital, University of Athens, Medical School, Athens, Greece

4. University of Athens, 1st Department of Cardiology, Hippokrateion Hospital, Athens, Greece

Abstract

AbstractAntihypertensive drugs namely angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, calcium channel blockers, beta blockers, and diuretics are among the most clearly documented regimens worldwide with an overall cardioprotective benefit. Given that malignancy is the second leading cause of mortality, numerous observational studies aimed to investigate the carcinogenic potential of these agents with conflicting results. The purpose of this review was to summarize current data in an effort to explore rare side effects and new mechanisms linking antihypertensive drugs with the risk of developing cancer.

Publisher

Oxford University Press (OUP)

Subject

Internal Medicine

Link

http://academic.oup.com/ajh/advance-article-pdf/doi/10.1093/ajh/hpaa098/33530398/hpaa098.pdf

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