A population pharmacokinetic study of benzathine benzylpenicillin G administration in children and adolescents with rheumatic heart disease: new insights for improved secondary prophylaxis strategies

Author:

Hand Robert M1ORCID,Salman Sam2ORCID,Newall Nelly1,Vine Julie3,Page-Sharp Madhu4,Bowen Asha C125,Gray Katherine1,Baker Amy1,Kado Joseph1,Joseph John6,Marsh Julie1,Ramsay James7,Sika-Paotonu Dianne18910,Batty Kevin T4,Manning Laurens2,Carapetis Jonathan125

Affiliation:

1. Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, University of Western Australia, Perth, Western Australia, Australia

2. Faculty of Health and Medical Sciences, University of Western Australia, Perth, Western Australia, Australia

3. Department of Ambulatory Care, Perth Children’s Hospital, Perth, Western Australia, Australia

4. School of Pharmacy and Biomedical Sciences, Curtin University, Bentley, Western Australia, Australia

5. Department of Infectious Diseases, Perth Children’s Hospital, Perth, Western Australia, Australia

6. PathWest Laboratories, Nedlands, Perth, Western Australia, Australia

7. Department of Cardiology, Perth Children’s Hospital, Perth, Western Australia, Australia

8. Dean’s Department and Department of Pathology & Molecular Medicine, Wellington School of Medicine and Health Sciences, University of Otago, Wellington, New Zealand

9. Faculty of Health, Victoria University of Wellington, Wellington, New Zealand

10. Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand

Funder

National Health and Medical Research Council Early Career Fellowship

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology,Microbiology (medical)

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