Effects of tofacitinib in early arthritis-induced bone loss in an adjuvant-induced arthritis rat model

Author:

Vidal Bruno1,Cascão Rita1,Finnilä Mikko A J23,Lopes Inês P1,da Glória Vânia G1,Saarakkala Simo24,Zioupos Peter5,Canhão Helena6,Fonseca João Eurico17

Affiliation:

1. Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal

2. Research Unit of Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, Oulu, Finland

3. Department of Applied Physics, University of Eastern Finland, Kuopio, Finland

4. Medical Research Center, University of Oulu, Oulu, Finland

5. Biomechanics Laboratories, Cranfield Forensic Institute, Cranfield University, Defence Academy of the UK, Shrivenham, UK

6. CEDOC, EpiDoC Unit, NOVA Medical School and National School of Public Health, Universidade Nova de Lisboa, Lisboa, Portugal

7. Rheumatology Department, Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Lisbon Academic Medical Centre, Lisbon, Portugal

Funder

Pfizer

Publisher

Oxford University Press (OUP)

Subject

Pharmacology (medical),Rheumatology

Reference37 articles.

1. Epidemiology of adult rheumatoid arthritis;Alamanos;Autoimmun Rev,2005

2. Inflammatory cell infiltrate and RANKL/OPG expression in rheumatoid synovium: comparison with other inflammatory arthropathies and correlation with outcome;Fonseca;Clin Exp Rheumatol,2005

3. Osteoclast differentiation and activation;Boyle;Nature,2003

4. Cytokine pattern in very early rheumatoid arthritis favours B-cell activation and survival;Moura;Rheumatology,2011

5. Identification of a cytokine network sustaining neutrophil and Th17 activation in untreated early rheumatoid arthritis;Cascao;Arthritis Res Ther,2010

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