Disability, fatigue, pain and their associates in early diffuse cutaneous systemic sclerosis: the European Scleroderma Observational Study

Author:

Peytrignet Sébastien1,Denton Christopher P2,Lunt Mark1,Hesselstrand Roger3,Mouthon Luc4,Silman Alan5,Pan Xiaoyan1,Brown Edith1,Czirják László6,Distler Jörg H W7,Distler Oliver8,Fligelstone Kim2,Gregory William J9,Ochiel Rachel2,Vonk Madelon10,Ancuţa Codrina11,Ong Voon H2,Farge Dominique12,Hudson Marie1314,Matucci-Cerinic Marco15,Balbir-Gurman Alexandra16,Midtvedt Øyvind17,Jordan Alison C18,Stevens Wendy19,Moinzadeh Pia20,Hall Frances C21,Agard Christian22,Anderson Marina E23,Diot Elisabeth24,Madhok Rajan25,Akil Mohammed26,Buch Maya H2728,Chung Lorinda29,Damjanov Nemanja30,Gunawardena Harsha31,Lanyon Peter3233,Ahmad Yasmeen34,Chakravarty Kuntal35,Jacobsen Søren36,MacGregor Alexander J37,McHugh Neil38,Müller-Ladner Ulf39,Riemekasten Gabriela40,Becker Michael41,Roddy Janet42,Carreira Patricia E43,Fauchais Anne Laure44,Hachulla Eric45,Hamilton Jennifer46,İnanç Murat47,McLaren John S48,van Laar Jacob M49,Pathare Sanjay50,Proudman Susanna5152,Rudin Anna53,Sahhar Joanne54,Coppere Brigitte55,Serratrice Christine56,Sheeran Tom57,Veale Douglas J58,Grange Claire59,Trad Georges-Selim60,Herrick Ariane L16162

Affiliation:

1. Centre for Musculoskeletal Research, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK

2. Centre for Rheumatology and Connective Tissue Diseases, UCL Division of Medicine, Royal Free Campus, London, UK

3. Department of Rheumatology, Lund University, Lund, Sweden

4. Service de Médecine Interne, Hôpital Cochin, Centre de Référence pour les Vascularités Nécrosantes et la Sclérodermie Systémique, Université Paris Descartes, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France

5. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK

6. Department of Rheumatology and Immunology, Medical Center, University of Pécs, Pécs, Hungary, Erlangen, Germany

7. Department of Internal Medicine 3, University of Erlangen-Nuremberg, Erlangen, Germany

8. Department of Rheumatology, University of Zurich, Zurich, Switzerland

9. Rehabilitation Services, Salford Royal NHS Foundation Trust, Salford, UK

10. Department of the Rheumatic Diseases, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

11. Rheumatology 2 Department, Clinical Rehabilitation Hospital, ‘Grigore T. Popa’ University of Medicine and Pharmacy, Iaşi, Romania

12. Unité Clinique de Médecine Interne, Maladies Auto-immunes et Pathologie Vasculaire, Hôpital Saint-Louis, Paris, France

13. Lady Davis Institute, Jewish General Hospital, Montreal, Canada

14. Department of Medicine, McGill University, Montreal, Canada

15. Department Experimental and Clinical Medicine, Division Rheumatology AOUC, University of Florence, Florence, Italy

16. B. Shine Rheumatology Unit, Rambam Heath Care Campus, Rappaport Faculty of Medicine, Technion, Haifa, Israel

17. Rheumatology Unit, Oslo University Hospital Rikshospitalet, Oslo, Norway

18. Queen Elizabeth Hospital Birmingham, UHB Foundation Trust, Birmingham, UK

19. Rheumatology Unit, St Vincent’s Hospital, Melbourne, Australia

20. Department for Dermatology, University of Cologne, Köln, Germany

21. Department of Clinical Medicine, Cambridge University NHS Hospital Foundation Trust, Cambridge, UK

22. Department of Internal Medicine, Hôtel-Dieu Hospital, University of Nantes, Nantes, France

23. University of Liverpool, Aintree University Hospital, Liverpool, UK

24. Service de Médecine Interne, Hôpital Bretonneau Tours, Tours, France

25. Centre for Rheumatic Diseases, Royal Infirmary, Glasgow, UK

26. Department of Rheumatology, Sheffield Teaching Hospitals, Sheffield, UK

27. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK

28. NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, UK

29. Division of Immunology and Rheumatology, Stanford University, Stanford, CA, USA

30. Institute of Rheumatology, University of Belgrade School of Medicine, Belgrade, Serbia

31. Clinical and Academic Rheumatology, North Bristol NHS Trust, Bristol, UK

32. Rheumatology, Nottingham University Hospitals NHS Trust, Nottingham, UK

33. Rheumatology, Nottingham NHS Treatment Centre, Nottingham, UK

34. Peter Maddison Rheumatology Centre, Llandudno Hospital, Llandudno, UK

35. Department of Rheumatology, Queen’s Hospital, Romford, UK

36. Copenhagen Lupus and Vasculitis Clinic, Center for Rheumatology and Spine Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

37. Department of Medicine, Norwich Medical School, University of East Anglia, Norwich, UK

38. Department of Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, UK

39. Department of Rheumatology and Clinical Immunology, Justus-Liebig University Giessen, Kerckhoff Klinik, Bad Nauheim, Germany

40. Department of Rheumatology, University of Lübeck, Lübeck, Berlin, Germany

41. Department of Rheumatology and Clinical Immunology, University Hospital Charité Berlin, Berlin, Germany

42. Department of Rheumatology, Royal Perth Hospital, Perth, Australia

43. Servicio de Reumatologia, Hospital Universitario 12 de Octubre, Madrid, Spain

44. Internal Medicine Unit, Limoges University Hospital, Limoges, France

45. Centre National de Référence Maladies Systémiques et Auto-immunes Rares, Département de Médecine Interne et Immunologie Clinique, Université de Lille, Lille, France

46. Department of Rheumatology, Gateshead Hospitals Foundation Trust, Gateshead, UK

47. Department of Internal Medicine, Division of Rheumatology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey

48. Fife Rheumatic Diseases Unit, Whyteman’s Brae Hospital, Kirkcaldy, Scotland, UK

49. Department of Rheumatology and Clinical Immunology, UMC Utrecht, Utrecht, the Netherlands

50. Rheumatology, James Cook University Hospital, Middlesbrough, UK

51. Rheumatology Unit, Royal Adelaide Hospital

52. Discipline of Medicine, University of Adelaide, Adelaide, Australia

53. Department of Rheumatology and Inflammation Research, The Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden

54. Monash Centre for Inflammatory Diseases, Monash University, Melbourne, Australia

55. Department of Internal Medicine, Hôpital Edouard Herriot, Lyon, France

56. Department of Internal Medicine, Foundation Hospital Saint Joseph, Marseille, France

57. Department of Rheumatology, Cannock Chase Hospital, Cannock, UK

58. Rheumatology, St Vincent's University Hospital, Dublin, Ireland

59. Department of Internal Medicine 69310, Centre Hospitalier Lyon Sud, Pierre-Bénite, Lyon, France

60. Internal Medecine, Ambroise Paré Hospital, Boulogne, Billancourt, France

61. Salford Royal NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK

62. NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK

Funder

EULAR

European League Against Rheumatism

Publisher

Oxford University Press (OUP)

Subject

Pharmacology (medical),Rheumatology

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