Osteoprotegerin and receptor activator of nuclear factor kappaB ligand (RANKL) regulate osteoclast formation by cells in the human rheumatoid arthritic joint

Author:

Haynes D. R.,Crotti T. N.,Loric M.,Bain G. I.,Atkins G. J.,Findlay D. M.

Publisher

Oxford University Press (OUP)

Subject

Pharmacology (medical),Rheumatology

Reference24 articles.

1. Gravellese EM, Harada Y, Wang JT, Gorn AH, Thornhill TS, Goldring SR. Identification of cell types responsible for bone resorption in rheumatoid arthritis and juvenile rheumatoid arthritis. Am J Pathol1998;152:943–51.

2. Gough A, Sambrook P, Devlin J et al. Osteoclastic activation is the principal mechanism leading to secondary osteoporosis in rheumatoid arthritis. J Rheumatol1998; 25:1282–9.

3. Yasuda H, Shima N, Nakagawa N et al. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis‐inhibitory factor and is identical to TRANCE/RANKL. Proc Natl Acad Sci USA1998; 95:3597–602.

4. Lacey DL, Timms E, Tan HL et al. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell1998;9:165–76.

5. Simonet WS, Lacey DL, Dunstan CR et al. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell1997;89:309–19.

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