British Society for Rheumatology guideline on management of adult and juvenile onset Sjögren disease

Author:

Price Elizabeth J1ORCID,Benjamin Stuart2,Bombardieri Michele34,Bowman Simon567,Carty Sara1,Ciurtin Coziana8ORCID,Crampton Bridget9,Dawson Annabel10,Fisher Benjamin A1112ORCID,Giles Ian8,Glennon Peter13,Gupta Monica14,Hackett Katie L15ORCID,Larkin Genevieve16,Ng Wan-Fai1718,Ramanan Athimalaipet V1920,Rassam Saad21,Rauz Saaeha2223,Smith Guy24,Sutcliffe Nurhan25ORCID,Tappuni Anwar26,Walsh Stephen B27

Affiliation:

1. Department of Rheumatology, Great Western Hospital NHS Foundation Trust , Swindon, UK

2. The Academy Library and Information Service, Great Western Hospital NHS Foundation Trust , Swindon, UK

3. Department of Rheumatology, Barts and The London School of Medicine and Dentistry, Barts Health NHS Trust , London, UK

4. Centre for Experimental Medicine and Rheumatology, The William Harvey Research Institute, Queen Mary University of London , London, UK

5. Department of Rheumatology, Milton Keynes University Hospital , Milton Keynes, UK

6. Department of Rheumatology, University Hospitals Birmingham NHSFT , Birmingham, UK

7. Institute of Inflammation and Ageing, University of Birmingham , Birmingham, UK

8. Centre for Rheumatology, Division of Medicine, University College London , London, UK

9. Patient Representative, Sjogren’s UK Helpline Lead, Sjogren’s UK (British Sjögren’s Syndrome Association) , Birmingham, UK

10. Patient Representative, Sjogren’s UK (British Sjögren’s Syndrome Association) , Birmingham, UK

11. Rheumatology Research Group, Institute of Inflammation and Ageing, University of Birmingham , Birmingham, UK

12. National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre and Department of Rheumatology, University Hospitals Birmingham NHS Foundation Trust , Birmingham, UK

13. General Practice, NHS Staffordshire & Stoke on Trent ICB , Stafford, UK

14. Department of Rheumatology, Gartnavel General Hospital , Glasgow, UK

15. Department of Social Work, Education and Community Wellbeing, Northumbria University , Newcastle upon Tyne, UK

16. Department of Ophthalmology, Kings College Hospital , London, UK

17. Translational and Clinical Research Institute & Newcastle NIHR Biomedical Research Centre, Newcastle University , Newcastle upon Tyne, UK

18. Department of Rheumatology, Newcastle upon Tyne NHS Foundation Trust , Newcastle upon Tyne, UK

19. Department of Paediatric Rheumatology, Bristol Royal Hospital for Children , Bristol, UK

20. Translational Health Sciences, University of Bristol , Bristol, UK

21. Haematology and Haemato-Oncology, KIMS Hospital , Maidstone, Kent, UK

22. Ophthalmology, Institute of Inflammation and Ageing, University of Birmingham , Birmingham, UK

23. Birmingham and Midland Eye Centre, Sandwell and West Birmingham NHS Trust , Birmingham, UK

24. Department of Ophthalmology, Great Western Hospital NHS Foundation Trust , Swindon, UK

25. Department of Rheumatology, Barts Health NHS Trust , London, UK

26. Institute of Dentistry, Queen Mary University of London , London, UK

27. London Tubular Centre, University College London , London, UK

Abstract

Abstract Sjögren disease (SD) is a chronic, autoimmune disease of unknown aetiology with significant impact on quality of life. Although dryness (sicca) of the eyes and mouth are the classically described features, dryness of other mucosal surfaces and systemic manifestations are common. The key management aim should be to empower the individual to manage their condition—conserving, replacing and stimulating secretions; and preventing damage and suppressing systemic disease activity. This guideline builds on and widens the recommendations developed for the first guideline published in 2017. We have included advice on the management of children and adolescents where appropriate to provide a comprehensive guideline for UK-based rheumatology teams.

Publisher

Oxford University Press (OUP)

Reference346 articles.

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3. SAT0736-HPR “like a bag of liquorice allsorts—everybody's got different flavours”: a qualitative focus group study to explore symptoms of fatigue, sleep disturbances and pain in primary Sjögren's syndrome patients and to develop a future model of care;Hackett;Ann Rheum Dis,2017

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