Symptoms associated with inflammatory arthritis are common in the primary care population: results from the joint symptoms survey

Author:

Hider Samantha L12ORCID,Muller Sara1,Helliwell Toby1,Prior James A1,Scott Ian12,Lawton Sarah A1,Zwierska Irena1,van Schaardenburg Dirkjan3,van der Helm-van Mil Annette4,Raza Karim56,Mallen Christian D1

Affiliation:

1. Arthritis Research UK Primary Care Centre, Research Institute for Primary Care and Health Sciences, Keele University, Keele, UK

2. Haywood Academic Rheumatology Centre, Midlands Partnership Foundation Trust, Stoke-on-Trent, UK

3. Amsterdam Rheumatology and Immunology Center, Reade and Amsterdam University Medical Center, Amsterdam, Netherlands

4. Department of Rheumatology, Leids Universitair Medisch Centrum, Leiden, Netherlands

5. Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK

6. Department of Rheumatology, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK

Abstract

Abstract Objectives To describe the prevalence of self-reported inflammatory joint symptoms, such as joint pain, stiffness and swelling, in UK primary care patients consulting for both musculoskeletal (MSK) and non-musculoskeletal (non-MSK) complaints. Methods A joint symptoms questionnaire survey was sent to 10 161 individuals, of whom 5050 had consulted for MSK problems. These were matched by age, gender and general practice to non-MSK consulters. Participants provided data on relevant symptoms such as joint pain, stiffness and swelling. The prevalence of these symptoms, their severity and impact were compared between MSK and non-MSK consulters. Results A total of 4549 adults responded to the survey (adjusted response 45.8%) of whom 52.3% consulted for a MSK problem. The mean (s.d.) age was 61.6 (14.8) years and 58.9% were female. Persistent (on at least half of the days in the last month) inflammatory symptoms were common even in non-MSK consulters, with 42% reporting joint pain, 36% reporting joint stiffness and 18% reporting joint swelling. This is in comparison with 62% reporting joint pain, 50% stiffness and 24% swelling among MSK consulters. Conclusions Although symptoms such as persistent joint pain, swelling and stiffness are predictive of inflammatory arthritis, large numbers of people consulting primary care for non-MSK reasons report these symptoms when asked by questionnaire. This compounds the challenges of diagnosing inflammatory arthritis in a non-specialist setting where new approaches are needed to ensure accurate, early diagnosis, facilitating a treat-to-target approach.

Funder

National Institute for Health Research

NIHR

Arthritis Research UK Primary Care Centre of Excellence at Keele University

NHS

Department of Health and Social Care

Publisher

Oxford University Press (OUP)

Subject

Pharmacology (medical),Rheumatology

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