IL-18 as therapeutic target in a patient with resistant systemic juvenile idiopathic arthritis and recurrent macrophage activation syndrome-Reference-Cited by-同舟云学术

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IL-18 as therapeutic target in a patient with resistant systemic juvenile idiopathic arthritis and recurrent macrophage activation syndrome

Published:2019-07-29 Issue:2 Volume:59 Page:442-445
ISSN:1462-0324
Container-title:Rheumatology
language:en
Short-container-title:

Author:

Yasin Shima¹,Solomon Krista¹,Canna Scott W²,Girard-Guyonvarc’h Charlotte³,Gabay Cem³,Schiffrin Eduardo⁴,Sleight Andrew⁴,Grom Alexei A¹,Schulert Grant S¹

Affiliation:

1. Division of Rheumatology, Cincinnati Children’s Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH

2. Pediatric Rheumatology & Immunology, Children’s Hospital of Pittsburgh/UPMC, Pittsburgh, PA, USA

3. Rheumatology, Geneva University Hospitals and University of Geneva, Geneva

4. AB2Bio, Lausanne, Switzerland

Funder

NIH

Publisher

Oxford University Press (OUP)

Subject

Pharmacology (medical),Rheumatology

Link

http://academic.oup.com/rheumatology/article-pdf/59/2/442/40420281/brheum_59_2_442.pdf

Reference8 articles.

1. Pathogenesis of macrophage activation syndrome and potential for cytokine- directed therapies;Schulert;Annu Rev Med,2015

2. Elevated serum levels of free interleukin-18 in adult-onset Still's disease;Girard;Rheumatology,2016

3. Distinct subsets of patients with systemic juvenile idiopathic arthritis based on their cytokine profiles;Shimizu;Cytokine,2013

4. High circulating levels of free interleukin-18 in patients with active SLE in the presence of elevated levels of interleukin-18 binding protein;Novick;J Autoimmun,2010

5. Life-threatening NLRC4-associated hyperinflammation successfully treated with IL-18 inhibition;Canna;J Allergy Clin Immunol,2017

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1. Long-term efficacy of MAS825, a bispecific anti-IL1β and IL-18 monoclonal antibody, in two patients with systemic JIA and recurrent episodes of macrophage activation syndrome;Rheumatology;2024-08-23

2. Maladies auto-inflammatoires associées à l’IL-18;La Revue de Médecine Interne;2024-08

3. The NLRP3 inflammasome is essential for IL-18 production in a murine model of macrophage activation syndrome;Disease Models & Mechanisms;2024-07-01

4. An antibody to IL-1 receptor 7 protects mice from LPS-induced tissue and systemic inflammation;Frontiers in Immunology;2024-06-25

5. Interleukin‑18 binding protein: Biological properties and roles in human and animal immune regulation (Review);Biomedical Reports;2024-04-09

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