Pharmacokinetic–pharmacodynamic correlations and biomarkers in the development of COX-2 inhibitors
Author:
Publisher
Oxford University Press (OUP)
Subject
Pharmacology (medical),Rheumatology
Link
http://academic.oup.com/rheumatology/article-pdf/44/7/846/9447295/keh627.pdf
Reference123 articles.
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3. Biomarkers Definitions Working Group. Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin Pharmacol Ther2001;69:89–95.
4. Rolan P. The contribution of clinical pharmacology surrogates and models to drug development—a critical appraisal. Br J Clin Pharmacol1997;44:219–25.
5. Vane JR. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol1971;231:232–5.
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