IL-6 trans-signalling directly induces RANKL on fibroblast-like synovial cells and is involved in RANKL induction by TNF- and IL-17
Author:
Publisher
Oxford University Press (OUP)
Subject
Pharmacology (medical),Rheumatology
Link
http://academic.oup.com/rheumatology/article-pdf/47/11/1635/5066082/ken363.pdf
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1. BONE RESORPTION BY TARTRATE-RESISTANT ACID PHOSPHATASE-POSITIVE MULTINUCLEAR CELLS ISOLATED FROM RHEUMATOID SYNOVIUM
2. Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor
3. Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation
4. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
5. RANK is essential for osteoclast and lymph node development
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