The rationale for Janus kinase inhibitors for the treatment of spondyloarthritis

Author:

Veale Douglas J12,McGonagle Dennis34,McInnes Iain B5,Krueger James G6,Ritchlin Christopher T7,Elewaut Dirk8,Kanik Keith S9,Hendrikx Thijs10,Berstein Gabriel11,Hodge Jennifer12,Telliez Jean-Baptiste11

Affiliation:

1. The Centre for Arthritis and Rheumatic Diseases, St Vincent’s University Hospital, Dublin, Ireland

2. University College, Dublin, Ireland

3. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, UK

4. NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK

5. Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK

6. Laboratory of Investigative Dermatology, The Rockefeller University, New York, USA

7. Allergy, Immunology & Rheumatology Division, University of Rochester Medical Center, Rochester, NY, USA

8. Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Center, Ghent University and Department of Rheumatology, Ghent University Hospital, Ghent, Belgium

9. Pfizer Inc, Groton, CT, USA

10. Pfizer Inc, Collegeville, PA, USA

11. Pfizer Inc, Cambridge, MA, USA

12. Pfizer Inc, New York, NY, USA

Funder

Pfizer Inc

Publisher

Oxford University Press (OUP)

Subject

Pharmacology (medical),Rheumatology

Reference72 articles.

1. Management and evaluation of extra-articular manifestations in spondyloarthritis;van der Horst-Bruinsma;Ther Adv Musculoskelet Dis,2012

2. Group for Research and Assessment of Psoriasis and Psoriatic Arthritis 2015 treatment recommendations for psoriatic arthritis;Coates;Arthritis Rheumatol,2016

3. Is there a need for new agents with novel mechanisms of action in psoriatic arthritis?;Orr;Ann Rheum Dis,2014

4. Therapeutic targeting of IL-17 and IL-23 cytokines in immune-mediated diseases;Fragoulis;Annu Rev Med,2016

5. ’MHC-I-opathy’-unified concept for spondyloarthritis and Behcet disease;McGonagle;Nat Rev Rheumatol,2015

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