Inhibition of nucleotide pyrophosphatase/phosphodiesterase 1: implications for developing a calcium pyrophosphate deposition disease modifying drug

Author:

Danino Ortal1,Svetitsky Shuli2,Kenigsberg Sarah1,Levin Asaf1,Journo Shani2,Gold Aviram3,Drexler Michael3,Snir Nimrod3,Elkayam Ori2,Fischer Bilha1,Arad Uri2

Affiliation:

1. Department of Chemistry, Bar-Ilan University, Ramat-Gan, Israel

2. Department of Rheumatology, Tel Aviv University, Tel Aviv, Israel

3. Division of Orthopedics, Tel Aviv Medical Center and the Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

Funder

Kamin Fund of the Israel Ministry of Trade and Industry

Publisher

Oxford University Press (OUP)

Subject

Pharmacology (medical),Rheumatology

Reference35 articles.

1. Update on calcium pyrophosphate deposition;Abhishek;Clin Exp Rheumatol,2016

2. Measuring functional disability in early rheumatoid arthritis: the validity, reliability and responsiveness of the Recent-Onset Arthritis Disability (ROAD) index;Salaffi;Clin Exp Rheumatol,2005

3. European League Against Rheumatism recommendations for calcium pyrophosphate deposition. Part I: terminology and diagnosis;Zhang;Ann Rheum Dis,2011

4. Methotrexate in chronic-recurrent calcium pyrophosphate deposition disease: no significant effect in a randomized crossover trial;Finckh;Arthritis Res Ther,2014

5. Inorganic pyrophosphate as a regulator of hydroxyapatite or calcium pyrophosphate dihydrate mineral deposition by matrix vesicles;Thouverey;Osteoarthritis Cartilage,2009

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