Growing evidence of the safety of JAK inhibitors in patients with rheumatoid arthritis

Author:

Harigai Masayoshi1

Affiliation:

1. Division of Epidemiology and Pharmacoepidemiology, Department of Rheumatology, School of Medicine, Tokyo Women’s Medical University, Tokyo, Japan

Funder

Tokyo Women’s Medical University

Ayumi Pharmaceutical Co.

Bristol Myers Squib

Chugai Pharmaceutical Co., Ltd

Eisai Co., Ltd

Nippon Kayaku Co., Ltd

Taisho Toyama Pharmaceutical Co., Ltd

Takeda Pharmaceutical Co., Ltd

Mitsubishi Tanabe Pharma Co.

Teijin Pharma Ltd

Gilead Sciences, Inc.

Abbvie Japan Co., Ltd

Bristol-Myers Squibb K.K.

Ono Pharmaceutical Co., Ltd

Santen Pharmaceutical Co., Ltd

Teijin Pharma, Ltd

Pfizer Japan Inc.

Publisher

Oxford University Press (OUP)

Subject

Pharmacology (medical),Rheumatology

Reference62 articles.

1. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update;Smolen;Ann Rheum Dis,2017

2. The emerging safety profile of JAK inhibitors in rheumatic disease;Winthrop;Nat Rev Rheumatol,2017

3. Safety and efficacy of tofacitinib, an oral Janus kinase inhibitor, for the treatment of rheumatoid arthritis in open-label, longterm extension studies;Wollenhaupt;J Rheumatol,2014

4. Tofacitinib, an oral Janus kinase inhibitor, in the treatment of rheumatoid arthritis: safety and efficacy in open-label, long-term extension studies over 9 years (Abstract 1647);Wollenhaupt;Arthritis Rheumatol,2017

5. Analysis of neutrophils, lymphocytes, and platelets in pooled phase 2 and phase 3 studies of baricitinib for rheumatoid arthritis (FRI0090);Kremer;Ann Rheum Dis,2017

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