GBA haploinsufficiency accelerates alpha-synuclein pathology with altered lipid metabolism in a prodromal model of Parkinson’s disease-Reference-Cited by-同舟云学术

GBA haploinsufficiency accelerates alpha-synuclein pathology with altered lipid metabolism in a prodromal model of Parkinson’s disease

Published:2019-01-28 Issue:11 Volume:28 Page:1894-1904
ISSN:0964-6906
Container-title:Human Molecular Genetics
language:en
Short-container-title:

Author:

Ikuno Masashi¹,Yamakado Hodaka¹,Akiyama Hisako²,Parajuli Laxmi Kumar³,Taguchi Katsutoshi⁴,Hara Junko¹,Uemura Norihito¹,Hatanaka Yusuke¹,Higaki Katsumi⁵,Ohno Kousaku⁶,Tanaka Masaki⁴,Koike Masato³,Hirabayashi Yoshio²,Takahashi Ryosuke¹

Affiliation:

1. Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan

2. Laboratory for Molecular Membrane Neuroscience, RIKEN Brain Science Institute, Saitama, Japan

3. Department of Cell Biology and Neuroscience, Juntendo University Graduate School of Medicine, Tokyo, Japan

4. Department of Anatomy and Neurobiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan

5. Division of Functional Genomics, Research Center for Bioscience and Technology, Faculty of Medicine, Tottori University, Tottori, Japan

6. Sanin Rosai Hospital, Tottori, Japan

Funder

JST

CREST

Grants-in-Aid for Scientific Research

AMED

MEXT

Brain/MINDS

Publisher

Oxford University Press (OUP)

Subject

Genetics(clinical),Genetics,Molecular Biology,General Medicine

Link

http://academic.oup.com/hmg/article-pdf/28/11/1894/28659031/ddz030.pdf

Reference30 articles.

1. Alpha-synuclein locus duplication as a cause of familial Parkinson's disease;Chartier-Harlin;Lancet,2004

2. Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease;Ibanez;Lancet,2004

3. alpha-synuclein locus triplication causes Parkinson's disease;Singleton;Science,2003

4. Genome-wide association study reveals genetic risk underlying Parkinson's disease;Simon-Sanchez;Nat. Genet.,2009

5. Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease;Satake;Nat. Genet.,2009

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