Evolutionary redesign of the lysosomal enzyme arylsulfatase A increases efficacy of enzyme replacement therapy for metachromatic leukodystrophy
Author:
Affiliation:
1. Institute of Biochemistry and Molecular Biology, Rheinische Friedrich-Wilhelms University, Bonn, Germany
Funder
Rheinische Friedrich-Wilhelms-Universität
Publisher
Oxford University Press (OUP)
Subject
Genetics (clinical),Genetics,Molecular Biology,General Medicine
Link
http://academic.oup.com/hmg/article-pdf/28/11/1810/28659076/ddz020.pdf
Reference37 articles.
1. Lysosomal storage diseases;Platt;Nat. Rev. Dis. Primers,2018
2. Enzyme replacement therapy for lysosomal diseases: lessons from 20 years of experience and remaining challenges;Desnick;Annu. Rev. Genomics Hum. Genet.,2012
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