A longitudinal multimodal in vivo molecular imaging study of the 3xTg-AD mouse model shows progressive early hippocampal and taurine loss

Author:

Chiquita Samuel12,Ribeiro Mário234,Castelhano João234,Oliveira Francisco234,Sereno José234,Batista Marta3,Abrunhosa Antero234,Rodrigues-Neves Ana C12,Carecho Rafael12,Baptista Filipa12,Gomes Catarina12,Moreira Paula I256,Ambrósio António F12ORCID,Castelo-Branco Miguel234ORCID

Affiliation:

1. Coimbra Institute for Clinical and Biomedical Research, Faculty of Medicine, University of Coimbra, Coimbra, Portugal

2. CNC.IBILI Consortium, University of Coimbra, Coimbra, Portugal

3. Coimbra Institute for Biomedical Imaging and Translational Research, University of Coimbra, Coimbra, Portugal

4. Institute for Nuclear Sciences Applied to Health, University of Coimbra, Coimbra, Portugal

5. Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal

6. Institute of Physiology, Faculty of Medicine, University of Coimbra, Coimbra, Portugal

Funder

Centro 2020 Regional Operational Programme

COMPETE-FEDER

Foundation for Science and Technology

Santa Casa Mantero Belard Award 2015

Publisher

Oxford University Press (OUP)

Subject

Genetics(clinical),Genetics,Molecular Biology,General Medicine

Reference66 articles.

1. Alzheimer’s disease;Ballard;Lancet,2011

2. Memory loss in Alzheimer’s disease;Jahn;Dialogues Clin. Neurosci.,2013

3. Transgenic mouse models of Alzheimer’ s disease;Christopher Janusa;Physiol. Behav.,2001

4. Genetically engineered mouse models of neurodegenerative diseases;Wong;Nat. Neurosci.,2002

5. Mouse models of neurological disorders––a comparison of heritable and acquired traits;Harper;Biochim. Biophys. Acta––Mol. Basis Dis.,2010

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