BMPRII deficiency impairs apoptosis via the BMPRII-ALK1-BclX-mediated pathway in pulmonary arterial hypertension-Reference-Cited by-同舟云学术

BMPRII deficiency impairs apoptosis via the BMPRII-ALK1-BclX-mediated pathway in pulmonary arterial hypertension

Published:2019-02-27 Issue:13 Volume:28 Page:2161-2173
ISSN:0964-6906
Container-title:Human Molecular Genetics
language:en
Short-container-title:

Author:

Chowdhury H M¹,Sharmin N²³,Yuzbasioglu Baran Merve²⁴,Long L⁵,Morrell N W⁵,Trembath R C¹⁶,Nasim Md Talat¹²⁶⁷

Affiliation:

1. Department of Medical and Molecular Genetics, King’s College London, London, United Kingdom

2. School of Pharmacy and Medical Sciences, University of Bradford, Bradford, United Kingdom

3. Department of Pharmaceutical Technology, University of Dhaka, Dhaka, Bangladesh

4. Department of Pharmacognosy, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey

5. Division of Respiratory Medicine, Department of Medicine, University of Cambridge, Cambridge, United Kingdom

6. National Institute for Health Research (NIHR), Biomedical Research Centre, Guy’s and St. Thomas’ NHS Foundation Trust and King’s College London, London, United Kingdom

7. Centre for Health Agricultural and Socio-economic Advancements (CHASA), Lalmonirhat, Bangladesh

Funder

Scientific and Technological Research Council of Turkey

Commonwealth Scholarship Commission

University of Bradford

Medical Research Council

Royal Society

Great Britain Sasakawa Foundation

Heptagon Life Science Proof of Concept Fund

King’s College London

Guy's and St Thomas' NHS Foundation Trust

National Institute for Health Research

Publisher

Oxford University Press (OUP)

Subject

Genetics (clinical),Genetics,Molecular Biology,General Medicine

Link

http://academic.oup.com/hmg/article-pdf/28/13/2161/28848044/ddz047.pdf

Reference43 articles.

1. Cellular and molecular basis of pulmonary arterial hypertension;Morrell;J. Am. Coll. Cardiol.,2009

2. Primary pulmonary hypertension;Gaine;Lancet,1998

3. Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension. The International PPH Consortium;Lane;Nat. Genet.,2000

4. Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension;Long;Nat. Med.,2015

5. Stoichiometric imbalance in the receptor complex contributes to dysfunctional BMPR-II mediated signalling in pulmonary arterial hypertension;Nasim;Hum. Mol. Genet.,2008

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