Ancient species offers contemporary therapeutics: an update on shark VNAR single domain antibody sequences, phage libraries and potential clinical applications
Author:
Affiliation:
1. NCI Antibody Engineering Program, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
2. Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
Abstract
Funder
National Institutes of Health
National Cancer Institute
NIH
Publisher
Oxford University Press (OUP)
Subject
Immunology,Immunology and Allergy
Link
http://academic.oup.com/abt/advance-article-pdf/doi/10.1093/abt/tbaa001/31888929/tbaa001.pdf
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4. The evolution of the immune response. XI. The immunoglobulins of the horned shark, Heterodontus francisci: purification, characterization and structural requirement for antibody activity;Frommel;J Immunol,1971
5. A cold-blooded view of adaptive immunity;Flajnik;Nat Rev Immunol,2018
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