Activation of mTORC1 Signaling Cascade in Hippocampus and Medial Prefrontal Cortex Is Required for Antidepressant Actions of Vortioxetine in Mice
Author:
Affiliation:
1. Department of Pharmacology, School of Pharmacy, Nantong University , Nantong, Jiangsu , China
2. Institute of Interdisciplinary Integrative Medicine Research, Medical School of Nantong University, Nantong , Jiangsu , China
Abstract
Funder
National Natural Science Foundation of China
Publisher
Oxford University Press (OUP)
Subject
Pharmacology (medical),Psychiatry and Mental health,Pharmacology
Link
https://academic.oup.com/ijnp/advance-article-pdf/doi/10.1093/ijnp/pyad017/50083970/pyad017.pdf
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4. New approaches to antidepressant drug discovery: beyond monoamines;Berton;Nat Rev Neurosci,2006
5. Ketamine enhances structural plasticity in mouse mesencephalic and human iPSC-derived dopaminergic neurons via AMPAR-driven BDNF and mTOR signaling;Cavalleri;Mol Psychiatry,2018
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