Synergistic activity of an OmpA inhibitor and colistin against colistin-resistant Acinetobacter baumannii: mechanistic analysis and in vivo efficacy

Author:

Parra-Millán Raquel1,Vila-Farrés Xavier23,Ayerbe-Algaba Rafael1,Varese Monica2,Sánchez-Encinales Viviana1,Bayó Nuría2,Pachón-Ibáñez María Eugenia1,Teixidó Meritxell2,Vila Jordi3ORCID,Pachón Jerónimo1,Giralt Ernest24,Smani Younes1ORCID

Affiliation:

1. Clinic Unit of Infectious Diseases Microbiology and Preventive Medicine, Institute of Biomedicine of Seville IBiS University Hospital Virgen del Rocío/CSIC/University of Seville, Seville, Spain

2. Institute for Research in Biomedicine (IRB Barcelona) Barcelona Institute for Science and Technology (BIST), Barcelona, Spain

3. Barcelona Centre for International Health Research (CRESIB Hospital Clínic-Universitat de Barcelona), Barcelona, Spain

4. Faculty of Chemistry, University of Barcelona, Barcelona, Spain

Funder

Consejería de Salud y Bienestar Social

Consejería de Economía, Innovación, Ciencia y Empleo

Andalusia, Spain, by the Instituto de Salud Carlos III, Ministerio de Economía, Industria y Competitividad

Spanish Network for Research in Infectious Diseases

Ministerio de Economía, Industria y Competitividad

Generalitat de Catalunya

Ministerio de Economía y Competitividad of Spain

MINECO

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology,Microbiology (medical)

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