Alternatives to Transfusion

Author:

Bachert Sara Emily1,Dogra Prerna2,Boral Leonard I1

Affiliation:

1. Department of Pathology and Laboratory Medicine, University of of Kentucky Medical Center, Lexington

2. Department of Medicine, University of Kentucky, Lexington

Abstract

Abstract Objectives We discuss two main categories of blood substitutes: perfluorocarbons and hemoglobin-based oxygen carriers. Methods We provide a review of the notable products developed in both categories and include their attributes as well as their setbacks. Results We contribute a case report tothe growing literature of the successful use of Sanguinate. Conclusions We find that artificial oxygen carriers are an attractive field of research because of the practical limitations and the multitude of potential complications that surround human blood transfusions.

Publisher

Oxford University Press (OUP)

Subject

General Medicine

Reference23 articles.

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2. A review of blood substitutes: examining the history, clinical trial results, and ethics of hemoglobin-based oxygen carriers;Chen;Clinics (Sao Paulo).,2009

3. Artificial oxygen carriers as red blood cell substitutes: a selected review and current status;Kim;Artif Organs.,2004

4. Blood substitutes. Artificial oxygen carriers: perfluorocarbon emulsions;Spahn;Crit Care.,1999

5. Blood substitutes: fluorocarbon approach.;Riess,2007

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