DataMed – an open source discovery index for finding biomedical datasets

Author:

Chen Xiaoling1,Gururaj Anupama E1,Ozyurt Burak2,Liu Ruiling1,Soysal Ergin1,Cohen Trevor1,Tiryaki Firat1,Li Yueling2,Zong Nansu3,Jiang Min1,Rogith Deevakar1,Salimi Mandana1,Kim Hyeon-eui3,Rocca-Serra Philippe4,Gonzalez-Beltran Alejandra4,Farcas Claudiu3,Johnson Todd1,Margolis Ron5,Alter George6,Sansone Susanna-Assunta4,Fore Ian M5,Ohno-Machado Lucila3,Grethe Jeffrey S2,Xu Hua1

Affiliation:

1. School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA

2. Center for Research in Biological Systems

3. Department of Biomedical Informatics, University of California San Diego, La Jolla, CA, USA

4. e-Research Centre, University of Oxford, Oxford, UK

5. National Institutes of Health, Bethesda, MD, USA

6. University of Michigan, Ann Arbor, MI, USA

Abstract

Abstract Objective Finding relevant datasets is important for promoting data reuse in the biomedical domain, but it is challenging given the volume and complexity of biomedical data. Here we describe the development of an open source biomedical data discovery system called DataMed, with the goal of promoting the building of additional data indexes in the biomedical domain. Materials and Methods DataMed, which can efficiently index and search diverse types of biomedical datasets across repositories, is developed through the National Institutes of Health–funded biomedical and healthCAre Data Discovery Index Ecosystem (bioCADDIE) consortium. It consists of 2 main components: (1) a data ingestion pipeline that collects and transforms original metadata information to a unified metadata model, called DatA Tag Suite (DATS), and (2) a search engine that finds relevant datasets based on user-entered queries. In addition to describing its architecture and techniques, we evaluated individual components within DataMed, including the accuracy of the ingestion pipeline, the prevalence of the DATS model across repositories, and the overall performance of the dataset retrieval engine. Results and Conclusion Our manual review shows that the ingestion pipeline could achieve an accuracy of 90% and core elements of DATS had varied frequency across repositories. On a manually curated benchmark dataset, the DataMed search engine achieved an inferred average precision of 0.2033 and a precision at 10 (P@10, the number of relevant results in the top 10 search results) of 0.6022, by implementing advanced natural language processing and terminology services. Currently, we have made the DataMed system publically available as an open source package for the biomedical community.

Funder

NIH

National Institute of Allergy and Infectious Diseases

Publisher

Oxford University Press (OUP)

Subject

Health Informatics

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