Virtualization of open-source secure web services to support data exchange in a pediatric critical care research network

Author:

Frey Lewis J1,Sward Katherine A2,Newth Christopher JL3,Khemani Robinder G3,Cryer Martin E4,Thelen Julie L5,Enriquez Rene5,Shaoyu Su5,Pollack Murray M6,Harrison Rick E7,Meert Kathleen L8,Berg Robert A9,Wessel David L10,Shanley Thomas P11,Dalton Heidi12,Carcillo Joseph13,Jenkins Tammara L14,Dean J Michael15

Affiliation:

1. Biomedical Informatics Center, Department Public Health Sciences, Medical University of South Carolina, Charleston, USA

2. College of Nursing; Department of Biomedical Informatics, University of Utah, Salt Lake City, USA

3. USC Keck School of Medicine; Department of Anesthesiology and Critical Care Medicine, Children's Hospital Los Angeles, Los Angeles, USA

4. Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, USA

5. Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, USA

6. Phoenix Children’s Hospital, Department of Pediatrics, University of Arizona Phoenix, Phoenix, USA

7. Department of Pediatrics, University of California at Los Angeles, Los Angeles, USA

8. Department of Pediatrics, Children’s Hospital of Michigan, Detroit, USA

9. Department of Anesthesiology and Critical Care, The Children’s Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA

10. Department of Pediatrics, Children’s National Medical Center, Washington, DC, USA

11. Department of Pediatrics, University of Michigan, Ann Arbor, USA

12. Department of Child Health, Phoenix Children’s Hospital, University of Arizona College of Medicine-Phoenix, Phoenix, USA

13. Department of Critical Care Medicine, Children’s Hospital of Pittsburgh, Pittsburgh, USA

14. Eunice Kennedy Shriver National Institutes of Child Health and Human Development (NICHD), National Institutes of Health, Bethesda, USA

15. Department of Pediatrics, Division of Pediatric Critical Care Medicine, University of Utah School of Medicine; NICHD Collaborative Pediatric Critical Care Research Network, Salt Lake City, USA

Abstract

Abstract Objectives To examine the feasibility of deploying a virtual web service for sharing data within a research network, and to evaluate the impact on data consistency and quality. Material and Methods Virtual machines (VMs) encapsulated an open-source, semantically and syntactically interoperable secure web service infrastructure along with a shadow database. The VMs were deployed to 8 Collaborative Pediatric Critical Care Research Network Clinical Centers. Results Virtual web services could be deployed in hours. The interoperability of the web services reduced format misalignment from 56% to 1% and demonstrated that 99% of the data consistently transferred using the data dictionary and 1% needed human curation. Conclusions Use of virtualized open-source secure web service technology could enable direct electronic abstraction of data from hospital databases for research purposes.

Publisher

Oxford University Press (OUP)

Subject

Health Informatics

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