Proceedings of the 1st biannual bridging the gaps in lung cancer conference

Author:

Florez Narjust1ORCID,Patel Sandip P2,Wakelee Heather3,Bazhenova Lyudmila4,Massarelli Erminia5,Salgia Ravi5,Stiles Brendon6,Peters Solange7ORCID,Malhotra Jyoti8,Gadgeel Shirish M9,Nieva Jorge J10,Afkhami Michelle11ORCID,Hirsch Fred R12,Gubens Matthew13,Cascone Tina14,Levy Benjamin15,Sabari Joshua16,Husain Hatim17,Ma Patrick C18,Backhus Leah M19,Iyengar Puneeth20,Lee Percy21,Miller Russell17,Sands Jacob1,Kim Edward5

Affiliation:

1. Dana-Farber Cancer Institute, Harvard University School of Medicine , Boston, MA , United States

2. Sanford Stem Cell Clinical Center and San Diego Center for Precision Immunotherapy, University of California San Diego , La Jolla, CA , United States

3. Stanford University School of Medicine and Stanford Cancer Institute , Stanford, CA , United States

4. University of California San Diego Moores Cancer Center , La Jolla, CA ,  United States

5. Department of Medical Oncology & Therapeutics Research , City of Hope, Duarte, CA , United States

6. Cardiovascular and Vascular Surgery, Albert Einstein College of Medicine , Bronx, NY , United States

7. Medical Oncology, Lausanne University Hospital , Lausanne Vaud , Switzerland

8. Thoracic Medical Oncology , City of Hope Orange County, Irvine, CA , United States

9. Henry Ford Cancer Institute, Henry Ford Health Center , Detroit, MI ,  United States

10. Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California , Los Angeles, CA , United States

11. Department of Pathology, City of Hope Comprehensive Cancer Center , Duarte, CA , United States

12. Icahn School of Medicine and Center for Thoracic Oncology, Mount Sinai Health System , New York, NY , United States

13. Thoracic Medical Oncology, University of California San Francisco , San Francisco, CA , , United States

14. University of Texas MD Anderson Cancer Center , United States

15. Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine , Baltimore MD , United States

16. Langone Health Perlmutter Cancer Center and NYU Langone Grossman School of Medicine , New York, NY , United States

17. University of California San Diego , San Diego, CA , United States

18. Penn State Cancer Institute, Milton S. Hershey Medical Center and Penn State College of Medicine , Hershey, PA , United States

19. Department of Cardiothoracic Surgery, Standford University , Palo Alto, CA , United States

20. Memorial Sloan Kettering Cancer Center , New York, NY , United States

21. City of Hope National Medical Center , Los Angeles, CA , United States

Abstract

Abstract Lung cancer is the leading cause of cancer death in the US and globally. The mortality from lung cancer has been declining, due to a reduction in incidence and advances in treatment. Although recent success in developing targeted and immunotherapies for lung cancer has benefitted patients, it has also expanded the complexity of potential treatment options for health care providers. To aid in reducing such complexity, experts in oncology convened a conference (Bridging the Gaps in Lung Cancer) to identify current knowledge gaps and controversies in the diagnosis, treatment, and outcomes of various lung cancer scenarios, as described here. Such scenarios relate to biomarkers and testing in lung cancer, small cell lung cancer, EGFR mutations and targeted therapy in non-small cell lung cancer (NSCLC), early-stage NSCLC, KRAS/BRAF/MET and other genomic alterations in NSCLC, and immunotherapy in advanced NSCLC.

Publisher

Oxford University Press (OUP)

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