In Reply to “Pathogenic/Likely Pathogenic Somatic CDK12 Mutations in Black Men With Prostate Cancer”

Author:

Valle Luca F12,Nickols Nicholas G1234,Yamoah Kosj56ORCID,Garraway Isla P134,Maxwell Kara N789,Lynch Julie A101112

Affiliation:

1. Veterans Affairs Greater Los Angeles Healthcare System , Los Angeles, CA , USA

2. Department of Radiation Oncology, David Geffen School of Medicine at the University of California Los Angeles , Los Angeles, CA , USA

3. UCLA Jonsson Comprehensive Cancer Center , Los Angeles, CA , USA

4. Department of Urology, David Geffen School of Medicine at the University of California , Los Angeles, CA , USA

5. Department of Radiation Oncology, H. Lee Moffitt Cancer Center & Research Institute , Tampa, FL , USA

6. James A. Haley Veterans’ Hospital , Tampa, FL , USA

7. Division of Hematology/Oncology, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania , Philadelphia, PA , USA

8. Corporal Michael J. Crescenz Veterans Affairs Medical Center , Philadelphia, PA , USA

9. Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania , Philadelphia, PA , USA

10. Department of Veterans Affairs Informatics and Computing Infrastructure, Department of Veterans Affairs Salt Lake City Health Care System , Salt Lake City, UT , USA

11. Division of Epidemiology, Department of Internal Medicine, University of Utah School of Medicine , Salt Lake City, UT , USA

12. Department of Nursing and Health Sciences, University of Massachusetts , Boston, MA , USA

Abstract

This letter to the editor responds to comments by Sartor et al regarding recent findings on the clinical relevance of CDK12 pathogenic mutations.

Funder

U.S. Department of Veterans Affairs

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

Reference3 articles.

1. Pathogenic/likely pathogenic somatic CDK12 mutations in Black men with prostate cancer;Sartor

2. Comparison of circulating tumor DNA between African American and Caucasian patients with metastatic castrate-resistant prostate cancer post-abiraterone and/or enzalutamide;Jang,2023

3. Actionable genomic alterations in prostate cancer among Black and White United States veterans;Valle,2023

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