Evidence Regarding Pharmacogenetics in Pain Management and Cancer-Reference-Cited by-同舟云学术

Evidence Regarding Pharmacogenetics in Pain Management and Cancer

Published:2023-01-30 Issue:3 Volume:28 Page:189-192
ISSN:1083-7159
Container-title:The Oncologist
language:en
Short-container-title:

Author:

Smith D Max¹²^ORCID,Figg William D³^ORCID

Affiliation:

1. MedStar Genetic Medicine, MedStar Health , Columbia, MD , USA

2. Department of Oncology, Georgetown University Medical Center , Washington, DC , USA

3. Molecular Pharmacology Section, Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health , Bethesda, MD , USA

Abstract

AbstractPatients experience interindividual variation in response to analgesics, which may be partially explained by genetics. This commentary discusses a recently published trial on COMT genotype and opioid dose requirements and describes the potential role for COMT and other genes (eg, CYP2D6) on opioid therapy and the current evidence for germline pharmacogenetics and resources for opioid pharmacogenetics.

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

Link

https://academic.oup.com/oncolo/article-pdf/28/3/189/49806786/oyac277.pdf

Reference38 articles.

1. National patterns in prescription opioid use and misuse among cancer survivors in the United States;Jairam;JAMA Netw Open,2020

2. Pharmacogenomics;Roden;Lancet.,2019

3. Pharmacogenetics: a precision medicine approach to combatting the opioid epidemic;Smith;J Am Coll Clin Pharm,2021

4. Morphine versus oxycodone for cancer pain using a catechol-O-methyltransferase genotype biomarker: a multicenter, randomized, open-label, phase III clinical trial (RELIEF Study);Matsuoka;Oncologist

5. Selection of opioids for cancer-related pain using a biomarker: a randomized, multi-institutional, open-label trial (RELIEF study);Matsuoka;BMC Cancer,2017

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Predictive Model for Opioid Use Disorder in Chronic Pain: A Development and Validation Study;Biomedicines;2024-09-10