Calls to action on lung cancer management and research

Author:

Meyer May-Lucie1ORCID,Hirsch Fred R1ORCID,Bunn Paul A2,Ujhazy Peter3,Fredrickson David4,Berg Christine D5,Carbone David P6,Halmos Balazs7ORCID,Singh Harpreet8,Borghaei Hossein9ORCID,Ferris Andrea10,Langer Corey11ORCID,Dacic Sanja12,Mok Tony S13,Peters Solange14ORCID,Johnson Bruce E15

Affiliation:

1. Hematology and Oncology Department, Tisch Cancer Institute at Mount Sinai, Icahn School of Medicine and Thoracic Oncology Center , New York, NY, United States

2. Division of Medical Oncology, University of Colorado School of Medicine , Aurora, CO, United States

3. National Cancer Institute Translational Research Program, Division of Cancer Treatment and Diagnosis, , Rockville, MD, United States

4. Astra Zeneca , Washington, DC, United States

5. Early Cancer Detection Consultant , Bethesda, MD, United States

6. The Ohio State University—James Comprehensive Cancer Center Division of Medical Oncology, , Columbus, OH, United States

7. Department of Oncology, Montefiore Medical Center, Albert Einstein College of Medicine , Bronx, NY, United States

8. US Food and Drug Administration (FDA) , Washington, DC, United States

9. Fox Chase Cancer Center , Philadelphia, PA , United States

10. LUNGevity Foundation , Chicago, IL, United States

11. University of Pennsylvania Abramson Cancer Center, Perelman School of Medicine, , Philadelphia, PA, United States

12. Yale School of Medicine Department of Pathology, , New Haven, CT, United States

13. The Chinese University of Hong Kong State Laboratory of Translational Oncology, , Hong Kong, People’s Republic of China

14. University Hospital CHUV Department of Oncology, , Lausanne, Switzerland

15. Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School , Boston, MA , United States

Abstract

Abstract Lung cancer, the leading cause of cancer-related deaths globally, remains a pressing health issue despite significant medical advances. The New York Lung Cancer Foundation brought together experts from academia, the pharmaceutical and biotech industries as well as organizational leaders and patient advocates, to thoroughly examine the current state of lung cancer diagnosis, treatment, and research. The goal was to identify areas where our understanding is incomplete and to develop collaborative public health and scientific strategies to generate better patient outcomes, as highlighted in our “Calls to Action.” The consortium prioritized 8 different calls to action. These include (1) develop strategies to cure more patients with early-stage lung cancer, (2) investigate carcinogenesis leading to lung cancers in patients without a history of smoking, (3) harness precision medicine for disease interception and prevention, (4) implement solutions to deliver prevention measures and effective therapies to individuals in under-resourced countries, (5) facilitate collaborations with industry to collect and share data and samples, (6) create and maintain open access to big data repositories, (7) develop new immunotherapeutic agents for lung cancer treatment and prevention, and (8) invest in research in both the academic and community settings. These calls to action provide guidance to representatives from academia, the pharmaceutical and biotech industries, organizational and regulatory leaders, and patient advocates to guide ongoing and planned initiatives.

Funder

NYLCF

Publisher

Oxford University Press (OUP)

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