Amyloid Network Topology Characterizes the Progression of Alzheimer’s Disease During the Predementia Stages

Author:

Pereira Joana B1,Strandberg Tor Olof23,Palmqvist Sebastian24,Volpe Giovanni5,van Westen Danielle67,Westman Eric1,Hansson Oskar23,

Affiliation:

1. Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm, Sweden

2. Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden

3. Memory Clinic, Skåne University Hospital, MalmöSweden

4. Department of Neurology, Skåne University Hospital, Sweden

5. Department of Physics, Göteborg University, Göteborg, Sweden

6. Department of Clinical Sciences Lund, Diagnostic Radiology, Lund University, Lund, Sweden

7. Imaging and Function, Skåne University Health Care, Lund, Sweden

Funder

National Institutes of Health

National Institute on Aging

National Institute of Biomedical Imaging and Bioengineering

Canadian Institutes of Health Research

Alzheimer’s Disease Neuroimaging Initiative

Alzheimer’s Association

Alzheimer’s Drug Discovery Foundation

BioClinica, Inc.

Biogen Idec Inc.

Bristol-Myers Squibb Company

Eisai Inc.

Elan Pharmaceuticals, Inc.

Eli Lilly and Company

F. Hoffmann-La Roche Ltd

Genentech, Inc.

GE Healthcare

Innogenetics, N.V.

IXICO Ltd.

Janssen Alzheimer Immunotherapy Research & Development, LLC.

Johnson & Johnson Pharmaceutical Research & Development LLC.

Medpace, Inc.

Merck & Co., Inc.

Meso Scale Diagnostics, LLC.

NeuroRx Research

Novartis Pharmaceuticals Corporation

Pfizer Inc.

Piramal Imaging

Servier

Synarc Inc.

Takeda Pharmaceutical Company

Northern California Institute for Research and Education

Alzheimer’s Disease Cooperative Study at the University of California, San Diego

Laboratory for Neuro Imaging at the University of California, Los Angeles

European Research Council

Swedish Research Council

Swedish Alzheimer Foundation

Swedish Brain Foundation

Marianne and Marcus Wallenberg Foundation

Swedish Foundation for Strategic Research (SSF)

Karolinska Institutet (StratNeuro)

Hjärnfonden

Birgitta och Sten Westerberg

Åke Wiberg Foundation

Swedish Federal Government

Publisher

Oxford University Press (OUP)

Subject

Cellular and Molecular Neuroscience,Cognitive Neuroscience

Reference63 articles.

1. Hierarchical organization of human cortical networks in health and schizophrenia;Bassett;J Neurosci,2008

2. Controlling the false discovery rate: a practical and powerful approach to multiple testing;Benjamini;J R Stat Soc Series B,1995

3. Amyloid biomarkers in alzheimer’s disease;Blennow;Trends Pharm Sci,2015

4. Neuropathological stageing of alzheimer-related changes;Braak;Acta Neuropathol,1991

5. The brain’s default network: anatomy, function, and relevance to disease;Buckner;Ann NY Acad Sci,2008

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