Abstract
Abstract
Neuroimaging studies have reported regions with more neural activation to face than nonface stimuli in the human occipitotemporal cortex for three decades. Here we used a highly sensitive and reliable frequency-tagging functional magnetic resonance imaging paradigm measuring high-level face-selective neural activity to assess interindividual variability in the localization and number of face-selective clusters. Although the majority of these clusters are located in the same cortical gyri and sulci across 25 adult brains, a volume-based analysis of unsmoothed data reveals a large amount of interindividual variability in their spatial distribution and number, particularly in the ventral occipitotemporal cortex. In contrast to the widely held assumption, these face-selective clusters cannot be objectively related on a one-to-one basis across individual brains, do not correspond to a single cytoarchitectonic region, and are not clearly demarcated by estimated posteroanterior cytoarchitectonic borders. Interindividual variability in localization and number of cortical face-selective clusters does not appear to be due to the measurement noise but seems to be genuine, casting doubt on definite labeling and interindividual correspondence of face-selective “areas” and questioning their a priori definition based on cytoarchitectony or probabilistic atlases of independent datasets. These observations challenge conventional models of human face recognition based on a fixed number of discrete neurofunctional information processing stages.
Funder
Excellence of Science
Fundamental Research Funds for the Central Universities of China
Zhejiang University Global Partnership Fund
Zhejiang University Startup Fund
Publisher
Oxford University Press (OUP)
Subject
Cellular and Molecular Neuroscience,Cognitive Neuroscience
Reference143 articles.
1. Social perception from visual cues: role of the STS region;Allison;Trends Cogn Sci,2000
2. Broca’s region revisited: cytoarchitecture and intersubject variability;Amunts;J Comp Neurol,1999
3. Activity in the fusiform gyrus predicts conscious perception of Rubin’s vase–face illusion;Andrews;Neuro Image,2002
4. The challenge of localizing the anterior temporal face area: a possible solution;Axelrod;Neuro Image,2013
5. Evaluating functional localizers: the case of the FFA;Berman;Neuro Image,2010
Cited by
9 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献