Neuronal and Peripheral Pentraxins Modify Glutamate Release and may Interact in Blood–Brain Barrier Failure

Author:

Cummings Damian M.1,Benway Tiffanie A.1,Ho Hinze12,Tedoldi Angelo13,Fernandes Freitas Monica M.1,Shahab Lion4,Murray Christina E.5,Richard-Loendt Angela6,Brandner Sebastian6,Lashley Tammaryn5,Salih Dervis A.1,Edwards Frances A.1

Affiliation:

1. Department of Neuroscience, Physiology & Pharmacology (NPP), University College London, London WC1E 6BT, UK

2. Present address: MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK

3. Present address: Queensland Brain Institute, The University of Queensland, St Lucia, QLD 4072, Australia

4. Department of Behavioural Science and Health, University College London, London WC1E 6BT, UK

5. The Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK

6. Division of Neuropathology and Department of Neurodegenerative Disease, Institute of Neurology, University College London, London WC1N 3BG, UK

Funder

MRC

UCL

Publisher

Oxford University Press (OUP)

Subject

Cellular and Molecular Neuroscience,Cognitive Neuroscience

Reference49 articles.

1. Neuronal pentraxin 1 contributes to the neuronal damage evoked by amyloid-beta and is overexpressed in dystrophic neurites in Alzheimer's brain;Abad;J Neurosci,2006

2. Amyloid-beta as a positive endogenous regulator of release probability at hippocampal synapses;Abramov;Nat Neurosci,2009

3. Differences in the acute phase responses of serum amyloid P-component (SAP) and C3 to injections of casein or bovine serum albumin in amyloid-susceptible and -resistant mouse strains;Baltz;Clin Exp Immunol,1980

4. Lack of widespread BBB disruption in Alzheimer's disease models: focus on therapeutic antibodies;Bien-Ly;Neuron,2015

5. Blood-brain barrier disturbance in patients with Alzheimer's disease is related to vascular factors;Blennow;Acta Neurol Scand,1990

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