Thr729 in human topoisomerase I modulates anti-cancer drug resistance by altering protein domain communications as suggested by molecular dynamics simulations-Reference-Cited by-同舟云学术

Thr729 in human topoisomerase I modulates anti-cancer drug resistance by altering protein domain communications as suggested by molecular dynamics simulations

Published:2008-09-02 Issue:17 Volume:36 Page:5645-5651
ISSN:1362-4962
Container-title:Nucleic Acids Research
language:en
Short-container-title:

Author:

Chillemi Giovanni,D’Annessa Ilda,Fiorani Paola,Losasso Carmen,Benedetti Piero,Desideri Alessandro

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

http://academic.oup.com/nar/article-pdf/36/17/5645/16748528/gkn558.pdf

Reference33 articles.

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2. The domain organization of human topoisomerase I;Stewart;J. Biol. Chem.,1996

3. Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA;Redinbo;Science,1998

4. Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme;Pommier;Biochim. Biophys. Acta,1998

5. A model for the mechanism of human topoisomerase I;Stewart;Science,1998

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