Correlates of Gait Speed Among Older Adults From 6 Countries: Findings From the COSMIC Collaboration

Author:

Sprague Briana N1ORCID,Zhu Xiaonan1,Rosso Andrea L1,Verghese Joe23ORCID,Delbaere Kim45ORCID,Lipnicki Darren M6ORCID,Sachdev Perminder S57ORCID,Ng Tze Pin8ORCID,Gwee Xinyi8,Yap Keng Bee9,Kim Ki-Woong101112,Han Ji Won1011,Oh Dae Jong1113,Narazaki Kenji14,Chen Tao15,Chen Sanmei16ORCID,Brodaty Henry6ORCID,Numbers Katya6,Kochan Nicole A6ORCID,Walker Richard W17,Paddick Stella-Maria18,Gureje Oye19,Ojagbemi Akin19,Bello Toyin19,Rosano Caterina1ORCID,

Affiliation:

1. Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh , Pittsburgh, Pennsylvania, USA

2. Department of Neurology, Albert Einstein College of Medicine , New York, New York , USA

3. Department of Medicine, Albert Einstein College of Medicine , New York, New York , USA

4. Falls, Balance and Injury Research Centre, Neuroscience Research Australia , Randwick, New South Wales , Australia

5. School of Population Health, University of New South Wales , Sydney, New South Wales , Australia

6. Centre for Healthy Brain Ageing (CHeBA), University of New South Wales , Sydney, New South Wales , Australia

7. Neuropsychiatric Institute, The Prince of Wales Hospital , Sydney, New South Wales , Australia

8. Department of Psychological Medicine, National University of Singapore , Singapore , Singapore

9. Department of Geriatric Medicine, Ng Teng Fong Hospital , Singapore , Singapore

10. Department of Neuropsychiatry, Seoul National University, Bundang Hospital , Seongnam , South Korea

11. Department of Psychiatry, Seoul National University College of Medicine , Seoul , South Korea

12. Department of Brain and Cognitive Sciences, Seoul National University College of Natural Sciences , Seoul , South Korea

13. Department of Psychiatry, SMG-SNU Boramae Medical Center , Seoul , South Korea

14. Center for Liberal Arts, Fukuoka Institute of Technology , Fukuoka , Japan

15. Sports and Health Research Center, Department of Physical Education, Tongji University , Shanghai , China

16. Department of Health Sciences, Graduate School of Biomedical and Health Sciences, Hiroshima University , Hiroshima , Japan

17. Department of Medicine, North Tyneside General Hospital , North Shields , UK

18. Translational and Clinical Research Institute; Newcastle University , Newcastle upon Tyne , UK

19. Department of Psychiatry, University of Ibadan , Ibadan , Nigeria

Abstract

Abstract Background Few studies have compared gait speed and its correlates among different ethnogeographic regions. The goals of this study were to describe usual and rapid gait speed, and identify their correlates across Australian, Asian, and African countries. Methods We used data from 6 population-based cohorts of adults aged 65+ from 6 countries and 3 continents (N = 6 472), with samples ranging from 231 to 1 913. All cohorts are members of the Cohort Studies of Memory in an International Consortium collaboration. We investigated whether clinical (body mass index [BMI], hypertension, stroke, apolipoprotein status), psychological (cognition, mood, general health), and behavioral factors (smoking, drinking, physical activity) correlated with usual (N = 4 cohorts) and rapid gait speed (N = 3 cohorts) similarly across cohorts. Regression models were controlled for age, sex, and education, and were sex-stratified. Results Age- and sex-standardized usual gait speed means ranged from 0.61 to 1.06 m/s and rapid gait speed means ranged from 1.16 to 1.64 m/s. Lower BMI and better cognitive function consistently correlated with faster gait speed in all cohorts. Less consistently, not having hypertension and greater physical activity engagement were associated with faster gait speed. Associations with mood, smoking, and drinking were largely nonsignificant. These patterns were not attenuated by demographics. There was limited evidence that the associations differed by sex, except physical activity, where the greater intensity was associated with usual gait among men but not women. Conclusions This study is among the first to describe the usual and rapid gait speeds across older adults in Africa, Asia, and Australia.

Funder

National Institute on Aging

Kirschstein Institutional National Research Service

Ministry for Health and & Welfare

Korean Health Industry Development Institute

Ministry of Health & Welfare and Ministry of Science and ICT

JSPS KAKENHI

Biomedical Research Council

National Medical Research Council

National Health & Medical Research Council

Publisher

Oxford University Press (OUP)

Subject

Geriatrics and Gerontology,Aging

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