Calorie Restriction-induced Weight Loss and Exercise Have Differential Effects on Skeletal Muscle Mitochondria Despite Similar Effects on Insulin Sensitivity
Author:
Affiliation:
1. Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pennsylvania
2. Translational Research Institute for Metabolism and Diabetes, Florida Hospital, Sanford–Burnham Medical Research Institute, Orlando
Funder
National Institute on Aging
University of Pittsburgh
the Obesity and Nutrition Research Center
the American Diabetes Association
Publisher
Oxford University Press (OUP)
Subject
Geriatrics and Gerontology,Ageing
Link
http://academic.oup.com/biomedgerontology/article-pdf/73/1/81/24371526/glw328.pdf
Reference41 articles.
1. Insulin resistance as a predictor of age-related diseases;Facchini;J Clin Endocrinol Metab,2001
2. Skeletal muscle insulin resistance is the primary defect in type 2 diabetes;DeFronzo;Diabetes Care,2009
3. High-fat diet, muscular lipotoxicity and insulin resistance;Schrauwen;Proc Nutr Soc,2007
4. Physical inactivity and obesity underlie the insulin resistance of aging;Amati;Diabetes Care,2009
5. Mitochondrial dysfunction in the elderly: possible role in insulin resistance;Petersen;Science,2003
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