Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline-Reference-Cited by-同舟云学术

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Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline

Published:2018-06-08 Issue:3 Volume:74 Page:290-298
ISSN:1079-5006
Container-title:The Journals of Gerontology: Series A
language:en
Short-container-title:

Author:

Valcarcel-Ares Marta Noa¹,Tucsek Zsuzsanna¹,Kiss Tamas¹,Giles Cory B¹²,Tarantini Stefano¹,Yabluchanskiy Andriy¹,Balasubramanian Priya¹,Gautam Tripti¹,Galvan Veronica³,Ballabh Praveen⁴,Richardson Arlan¹⁵,Freeman Willard M¹,Wren Jonathan D¹²,Deak Ferenc¹⁶,Ungvari Zoltan¹⁷,Csiszar Anna¹⁸

Affiliation:

1. Reynolds Oklahoma Center on Aging, Department of Geriatric Medicine, University of Oklahoma Health Sciences Center, Oklahoma City

2. Oklahoma Medical Research Foundation, Arthritis & Clinical Immunology Research Program, Oklahoma City

3. Barshop Institute for Longevity and Aging Studies and Department of Physiology, University of Texas Health Science Center at San Antonio

4. Division of Neonatology, Department of Pediatrics, Albert Einstein College of Medicine, Bronx, New York

5. Oklahoma City VA Medical Center, Oklahoma City

6. Oklahoma Center for Neuroscience, University of Oklahoma Health Sciences Center, Oklahoma City

7. Department of Medical Physics and Informatics, University of Szeged, Hungary

8. Department of Pulmonology, Semmelweis University, Budapest, Hungary

Funder

American Heart Association

National Institute on Aging

National Institute of Neurological Disorders and Stroke

NIH-supported Oklahoma Shared Clinical and Translational Resources

Oklahoma Center for the Advancement of Science and Technology

Presbyterian Health Foundation

Oklahoma Nathan Shock Aging Center

NIA-funded Geroscience Training Program in Oklahoma

EU-funded EFOP

Publisher

Oxford University Press (OUP)

Subject

Geriatrics and Gerontology,Aging

Link

http://academic.oup.com/biomedgerontology/article-pdf/74/3/290/27784048/gly127.pdf

Reference49 articles.

1. Forecasting the obesity epidemic in the aging U.S. population;Wang;Obesity (Silver Spring),2007

2. Obesity and central obesity as risk factors for incident dementia and its subtypes: a systematic review and meta-analysis;Beydoun;Obes Rev,2008

3. Relation of obesity to cognitive function: importance of central obesity and synergistic influence of concomitant hypertension. The Framingham Heart Study;Wolf;Curr Alzheimer Res,2007

4. Central obesity and increased risk of dementia more than three decades later;Whitmer;Neurology,2008

5. Body mass index and neurocognitive functioning across the adult lifespan;Stanek;Neuropsychology,2013

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