Genomic Characterization of Recent and Historic Meningococcal Serogroup E Invasive Disease in Australia: A Case Series

Author:

Thangarajah Dharshi12ORCID,Guglielmino Christine J D3,Lambert Stephen B14,Khandaker Gulam5,Vasant Bhakti R6,Malo Jonathan A1,Smith Helen V3,Jennison Amy V3

Affiliation:

1. Communicable Diseases Branch, Queensland Health, Brisbane

2. National Centre for Epidemiology and Population Health, Australian National University, Brisbane

3. Queensland Health Forensic and Scientific Services, Brisbane

4. Centre for Child Health Research, The University of Queensland, Brisbane

5. Central Queensland Public Health Unit, Queensland Health, Rockhampton, Australia

6. Metro South Public Health Unit, Queensland Health, Brisbane, Australia

Abstract

Abstract We report the recent emergence of invasive meningococcal disease due to serogroup E in Queensland, Australia, in previously healthy patients. Molecular typing revealed the genotype of these strains to be E:P1.21-7,16:F5-36:ST-1157 (cc1157); when analyzed phylogenetically, compared with international cc1157 strains, they were relatively unrelated to each other.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Reference16 articles.

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