The nerve of the spleen! Causing hypertension by placental growth factor

Author:

Van Beusecum Justin P1,Harrison David G1

Affiliation:

1. Division of Clinical Pharmacology, Department of Medicine, 2220 Pierce Ave, 536 Robinson Research Building, Vanderbilt University School of Medicine, Nashville, TN 37232-6602, USA

Funder

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

Reference10 articles.

1. Salt sensitivity of blood pressure: a scientific statement from the American Heart Association;Elijovich;Hypertension,2016

2. Deoxycorticosterone acetate-salt hypertension activates placental growth factor in the spleen to couple sympathetic drive and immune system activation;Perrotta;Cardiovasc Res,2018

3. The angiogenic factor PlGF mediates a neuroimmune interaction in the spleen to allow the onset of hypertension;Carnevale;Immunity,2014

4. Inhibition and genetic ablation of the B7/CD28 T-cell costimulation axis prevents experimental hypertension;Vinh;Circulation,2010

5. APC-derived cytokines and T cell polarization in autoimmune inflammation;Gutcher;J Clin Invest,2007

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