Author:
,Albertini David F,Crosignani PierGiorgio,Dumoulin John,Evers Johannes L H,Leridon Henri,Mastenbroek Sebastiaan,Painter Rebecca,Pinborg Anja,Somigliana Edgardo,Baird David T,Glasier Anna,La Vecchia Carlo,Albertini David F,Crosignani PierGiorgio,Dumoulin John,Evers Johannes L H,Leridon Henri,Mastenbroek Sebastiaan,Painter Rebecca,Pinborg Anja,Somigliana Edgardo,Baird David T,Glasier Anna,La Vecchia Carlo
Abstract
ABSTRACT
Today IVF use is booming all over the world and has even started to play a role in demographic analyses. Prognosis-adjusted estimates suggest that up to two-thirds of couples could achieve a live birth. However, the scenario is less exciting in reality. Discontinuation during the cycles is common, and age and ovarian response continue to be crucial in modulating this rate of success. A growing interest is now given to the risk of abuses and in particular to overtreatment and to prescriptions of useless, if not harmful, expensive additional treatments (‘add-ons’). A more rational, evidence-based and wise approach is needed. From a scientific perspective, several obscure aspects remain and warrant future investigations. Of particular interest are the neglected role of sperm selection, the potential adult implications of early embryo life in vitro and the issue of sustainability.
Funder
Institut Biochimique SA, Switzerland
Publisher
Oxford University Press (OUP)
Subject
Industrial and Manufacturing Engineering,Environmental Engineering