Recommendations for the Surgical Treatment of Endometriosis. Part 1: Ovarian Endometrioma†‡¶

Author:

,Saridogan Ertan1,Becker Christian M2,Feki Anis3,Grimbizis Grigoris F4,Hummelshoj Lone5,Keckstein Joerg6,Nisolle Michelle7,Tanos Vasilios8,Ulrich Uwe A9,Vermeulen Nathalie10,De Wilde Rudy Leon11

Affiliation:

1. Institute for Women's Health, University College Hospital, Reproductive Medicine Unit, Elizabeth Garrett Anderson Wing, London NW1 2BU, UK

2. University of Oxford, Endometriosis CaRe Centre, Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Women's Centre, Oxford OX3 9DU, UK

3. HFR Fribourg Hopital Cantonal, Department of Obstetrics and Gynecology, 1708 Fribourg, Switzerland

4. Medical School, Aristotle University of Thessaloniki, First Department of Obstetrics & Gynecology, Tsimiski 51 Street, 54623 Thessaloniki, Greece

5. World Endometriosis Society, London N1 3JS, UK

6. Landeskrankenanstalten-Betriebsgesellschaft (KABEG) and Landeskrankenhaus Villach, Abteilung für Gynäkologie und Geburtshilfe, 9500 Villach, Austria

7. Department of Obstetrics and Gynecology, Hôpital de la Citadelle, BE-4000 Liège, Belgium

8. Department of Obstetrics and Gynecology, Aretaeio Hospital, 2024 Nicosia, Cyprus

9. Martin-Luther Hospital, Department of Obstetrics and Gynecology/Endometriosis Center, 14193 Berlin, Germany

10. ESHRE, Central Office—Meerstraat 60, BE-1852 Grimbergen, Belgium

11. Carl von Ossietzky Universitat Oldenburg, University Hospital for Gynecology, DE-26129 Oldenburg, Germany

Abstract

Abstract STUDY QUESTION What does this document on the surgical treatment of endometriosis jointly prepared by the European Society for Gynaecological Endoscopy (ESGE), ESHRE, and the World Endometriosis Society (WES) provide? SUMMARY ANSWER This document provides recommendations covering technical aspects of different methods of surgery for endometriomas in women of reproductive age. WHAT IS ALREADY KNOWN Endometriomas (ovarian endometriotic cysts) are a commonly diagnosed form of endometriosis, owing to the relative ease and accuracy of ultrasound diagnosis. They frequently present a clinical dilemma as to whether and how to treat them when found during imaging or incidentally during surgery. Previously published guidelines have provided recommendations based on the best available evidence, but without technical details on the management of endometriosis. STUDY DESIGN SIZE, DURATION A working group of ESGE, ESHRE and WES collaborated on writing recommendations on the practical aspects of endometrioma surgery. PARTICIPANTS/MATERIALS, SETTING, METHODS This document focused on endometrioma surgery. Further documents in this series will provide recommendations for surgery of deep and peritoneal endometriosis. MAIN RESULTS AND THE ROLE OF CHANCE The document presents general recommendations for surgery of endometrioma, and specific recommendations for cystectomy, ablation by laser or by plasma energy, electrocoagulation and a combination of these techniques applied together or with an interval between them. LIMITATIONS REASONS FOR CAUTION Owing to the limited evidence available, recommendations are mostly based on clinical expertise. WIDER IMPLICATIONS OF THE FINDINGS These recommendations complement previous guidelines on the management of endometriosis. STUDY FUNDING/COMPETING INTERESTS The meetings of the working group were funded by ESGE, ESHRE and WES. C.B. declares to be a member of the independent data monitoring committee for a clinical study by ObsEva, and receiving research grants from Bayer, Roche Diagnostics, MDNA Life Sciences, and Volition. E.S. received honoraria for provision of training to healthcare professionals from Ethicon, Olympus and Gedeon Richter. The other authors declare that they have no conflict of interest. TRIAL REGISTRATION NUMBER NA.

Funder

European Society for Gynaecological Endoscopy

European Society of Human Reproduction and Embryology

World Endometriosis Society

Publisher

Oxford University Press (OUP)

Subject

Industrial and Manufacturing Engineering,Environmental Engineering

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