The crystal structure of homoserine dehydrogenase complexed withl-homoserine and NADPH in a closed form-Reference-Cited by-同舟云学术

The crystal structure of homoserine dehydrogenase complexed withl-homoserine and NADPH in a closed form

Published:2018-11-13 Issue:2 Volume:165 Page:185-195
ISSN:0021-924X
Container-title:The Journal of Biochemistry
language:en
Short-container-title:

Author:

Akai Shota¹,Ikushiro Hiroko²,Sawai Taiki²,Yano Takato²,Kamiya Nobuo¹³,Miyahara Ikuko¹

Affiliation:

1. Graduate School of Science, Osaka City University, Osaka, Japan

2. Depertment of Biochemistry, Faculty of Medicine, Osaka Medical College, Osaka, Japan

3. The OCU Advanced Research Institute for Natural Science and Technology, Osaka City University, Osaka, Japan

Funder

Grant-in-Aid for Scientific Research

Japan Society for the Promotion of Science

JSPS

Japan Foundation for Applied Enzymology

Toyo Institute of Food Technology

Japan Synchrotron Radiation Research Institute

JASRI

Publisher

Oxford University Press (OUP)

Subject

Molecular Biology,Biochemistry,General Medicine

Link

http://academic.oup.com/jb/article-pdf/165/2/185/27511946/mvy094.pdf

Reference31 articles.

1. Interaction of aspartate and aspartate-derived antimetabolites with the enzymes of the thereonine biosynthetic-pathway of Escherichia coli;Shames;J. Biol. Chem,1984

2. The aspartic acid metabolic pathway, an exciting and essential pathway in plants;Azevedo;Amino Acids,2006

3. Molecular control mechanisms of lysine and threonine biosynthesis in amino acid-producing corynebacteria: redirecting carbon flow;Malumbres;FEMS Microbiol. Lett,1996

4. Rational design of allosteric regulation of homoserine dehydrogenase by a nonnatural inhibitor l-lysine;Chen;ACS Synth. Biol.,2015

5. The mechanism of antifungal action of (S)-2-amino-4-oxo-5-hydroxypentanoic acid, RI-331—the inhibition of homoserine dehydrogenase in Saccharomyces cerevisiae;Yamaki;Biochem. Biophys. Res. Commun,1990

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