1. From the Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA (FLW); the Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA (FLW, JS, and MBL); and the Divisions of Nephrology (MBL) and Gastroenterology, Hepatology and Nutrition, The Children's Hospital