Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk

Author:

Painter Jodie N.1,O'Mara Tracy A.1,Batra Jyotsna2,Cheng Timothy3,Lose Felicity A.1,Dennis Joe4,Michailidou Kyriaki4,Tyrer Jonathan P.5,Ahmed Shahana5,Ferguson Kaltin1,Healey Catherine S.5,Kaufmann Susanne1,Hillman Kristine M.1,Walpole Carina2,Moya Leire2,Pollock Pamela6,Jones Angela3,Howarth Kimberley3,Martin Lynn3,Gorman Maggie3,Hodgson Shirley7,De Polanco Ma. Magdalena Echeverry8,Sans Monica9,Carracedo Angel1011,Castellvi-Bel Sergi12,Rojas-Martinez Augusto13,Santos Erika14,Teixeira Manuel R.1516,Carvajal-Carmona Luis3817,Shu Xiao-Ou18,Long Jirong18,Zheng Wei18,Xiang Yong-Bing19,Montgomery Grant W.1,Webb Penelope M.1,Scott Rodney J.202122,McEvoy Mark23,Attia John2023,Holliday Elizabeth2024,Martin Nicholas G.1,Nyholt Dale R.1,Henders Anjali K.1,Fasching Peter A.2526,Hein Alexander26,Beckmann Matthias W.26,Renner Stefan P.26,Dörk Thilo27,Hillemanns Peter28,Dürst Matthias29,Runnebaum Ingo29,Lambrechts Diether3031,Coenegrachts Lieve32,Schrauwen Stefanie32,Amant Frederic32,Winterhoff Boris33,Dowdy Sean C.33,Goode Ellen L.34,Teoman Attila33,Salvesen Helga B.3536,Trovik Jone3536,Njolstad Tormund S.3536,Werner Henrica M.J.3536,Ashton Katie2137,Proietto Tony38,Otton Geoffrey38,Tzortzatos Gerasimos39,Mints Miriam39,Tham Emma40,Hall Per41,Czene Kamila41,Liu Jianjun42,Li Jingmei42,Hopper John L.43,Southey Melissa C.44,Ekici Arif B.45,Ruebner Matthias26,Johnson Nicola46,Peto Julian47,Burwinkel Barbara4849,Marme Frederik4850,Brenner Hermann5152,Dieffenbach Aida K.5152,Meindl Alfons53,Brauch Hiltrud54,Lindblom Annika40,Depreeuw Jeroen30,Moisse Matthieu30,Chang-Claude Jenny55,Rudolph Anja56,Couch Fergus J.57,Olson Janet E.34,Giles Graham G.435859,Bruinsma Fiona58,Cunningham Julie M.57,Fridley Brooke L.60,Børresen-Dale Anne-Lise6162,Kristensen Vessela N.616263,Cox Angela64,Swerdlow Anthony J.6566,Orr Nicholas66,Bolla Manjeet K.4,Wang Qin4,Weber Rachel Palmieri67,Chen Zhihua68,Shah Mitul5,French Juliet D.1,Pharoah Paul D.P.5,Dunning Alison M.5,Tomlinson Ian3,Easton Douglas F.45,Edwards Stacey L.1,Thompson Deborah J.5,Spurdle Amanda B.1, , , , , ,

Affiliation:

1. QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia,

2. Australian Prostate Cancer Research Centre-Qld, Institute of Health and Biomedical Innovation, and School of Biomedical Science and,

3. Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK,

4. Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care and

5. Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK,

6. Institute of Health and Biomedical Innovation and School of Biomedical Science, Queensland University of Technology, Brisbane, QLD, Australia,

7. Department of Clinical Genetics, St George's Hospital Medical School, London, UK,

8. Grupo de Investigación Citogenética, Filogenia y Evolución de Poblaciones, Universidad del Tolima, Ibagué, Tolima, Colombia,

9. Department of Biological Anthropology, College of Humanities and Educational Sciences, University of the Republic, Magallanes, Montevideo, Uruguay,

10. Grupo de Medicina Xenómica, Fundación Galega de Medicina Xenómica (SERGAS) and CIBERER, Universidade de Santiago de Compostela, Santiago de Compostela, Spain,

11. Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, KSA,

12. Genetic Predisposition to Colorectal Cancer Group, Gastrointestinal & Pancreatic Oncology Team, IDIBAPS/CIBERehd/Hospital Clínic, Centre Esther Koplowitz (CEK), Barcelona, Spain,

13. Universidad Autónoma de Nuevo León, Pedro de Alba s/n, San Nicolás de Los Garza, Nuevo León, Mexico,

14. Hospital A.C. Camargo, São Paulo, Brazil,

15. Department of Genetics, Portuguese Oncology Institute, Porto, Portugal,

16. Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal,

17. Genome Center and Department of Biochemistry and Molecular Medicine, University of California, Davis, CA, USA,

18. Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA,

19. Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China,

20. Hunter Medical Research Institute and,

21. Hunter Area Pathology Service, John Hunter Hospital, Newcastle, NSW, Australia,

22. Centre for Information Based Medicine and School of Biomedical Science and Pharmacy,

23. Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health,

24. Centre for Information Based Medicine and School of Medicine and Public Health,

25. Division of Hematology/Oncology, Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA,

26. University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany,

27. Gynaecology Research Unit and,

28. Clinics of Gynaecology and Obstetrics, Hannover Medical School, Hannover, Germany,

29. Dept. of Gynaecology, Friedrich Schiller University Jena, Jena, Germany,

30. Vesalius Research Center, VIB, Leuven, Belgium,

31. Department of Oncology, Laboratory for Translational Genetics,

32. Division of Gynaecological Oncology, Department of Oncology, University Hospital Leuven, KU Leuven, Belgium,

33. Division of Gynecologic Oncology, Department of Obstetrics and Gynecology,

34. Division of Epidemiology, Department of Health Science Research and,

35. Department of Clinical Science, Centre for Cancerbiomarkers, The University of Bergen, Norway,

36. Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway,

37. Faculty of Health, Centre for Information Based Medicine and the Discipline of Medical Genetics, School of Biomedical Sciences and Pharmacy and,

38. Faculty of Health, School of Medicine and Public Health, University of Newcastle, NSW, Australia,

39. Department of Women's and Children's Health,

40. Department of Molecular Medicine and Surgery and

41. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden,

42. Human Genetics, Genome Institute of Singapore, Singapore,

43. Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health and

44. Department of Pathology, Genetic Epidemiology Laboratory, The University of Melbourne, Melbourne, VIC, Australia,

45. Institute of Human Genetics, University Hospital, Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany,

46. Breakthrough Breast Cancer Research Centre,

47. London School of Hygiene and Tropical Medicine, London, UK,

48. Molecular Biology of Breast Cancer, Department of Gynecology and Obstetrics,

49. Molecular Epidemiology, C080,

50. National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany,

51. Division of Clinical Epidemiology and Aging Research,

52. German Cancer Consortium (DKTK), Heidelberg, Germany,

53. Division of Tumor Genetics, Department of Obstetrics and Gynecology, Technical University of Munich, Munich, Germany,

54. Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology Stuttgart, University of Tuebingen, Germany,

55. Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany,

56. Department of Cancer Epidemiology/Clinical Cancer Registry and Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg, Germany,

57. Departments of Laboratory Medicine and Pathology, and Health Science Research, Mayo Clinic, Rochester, MN, USA,

58. Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, VIC, Australia,

59. Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, VIC, Australia,

60. Department of Biostatistics, University of Kansas Medical Center, Kansas City, KS, USA,

61. Department of Genetics, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway,

62. Faculty of Medicine, The K.G. Jebsen Center for Breast Cancer Research, Institute for Clinical Medicine, University of Oslo, Oslo, Norway,

63. Division of Medicine, Department of Clinical Molecular Oncology, Akershus University Hospital, Ahus, Norway,

64. Department of Oncology, Sheffield Cancer Research Centre, University of Sheffield, Sheffield, UK,

65. Division of Genetics and Epidemiology and,

66. Division of Breast Cancer Research, Institute of Cancer Research, London, UK,

67. Department of Community and Family Medicine, Duke University School of Medicine, Durham, NC, USA

68. Division of Population Sciences, Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL, USA

Publisher

Oxford University Press (OUP)

Subject

Genetics(clinical),Genetics,Molecular Biology,General Medicine

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3