LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA

Author:

Cruz-Gallardo Isabel1,Martino Luigi1,Kelly Geoff2,Atkinson R Andrew13,Trotta Roberta1,De Tito Stefano1,Coleman Pierre1,Ahdash Zainab4,Gu Yifei1,Bui Tam T T13,Conte Maria R13

Affiliation:

1. Randall Centre for Cell and Molecular Biophysics, King’s College London, London SE1 1UL, UK

2. MRC Biomedical NMR Centre, The Francis Crick Institute, London NW1 1AT, UK

3. Centre for Biomolecular Spectroscopy, King’s College London, London SE1 1UL, UK

4. Department of Chemistry, King’s College London, London SE1 1DB, UK

Funder

Newton Royal Society Fellowship

EU Horizon 2020 research and innovation programme Marie Sklodowska-Curie fellowship

EMBO long-term fellowship

Wellcome Trust and British Heart Foundation

Cancer Research UK

Medical Research Council

Wellcome Trust

Publisher

Oxford University Press (OUP)

Subject

Genetics

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