The moonlighting RNA-binding activity of cytosolic serine hydroxymethyltransferase contributes to control compartmentalization of serine metabolism

Author:

Guiducci Giulia1ORCID,Paone Alessio1ORCID,Tramonti Angela12ORCID,Giardina Giorgio1,Rinaldo Serena1,Bouzidi Amani1,Magnifico Maria C1,Marani Marina1,Menendez Javier A34,Fatica Alessandro5,Macone Alberto1,Armaos Alexandros6,Tartaglia Gian G5678,Contestabile Roberto1ORCID,Paiardini Alessandro1ORCID,Cutruzzolà Francesca1ORCID

Affiliation:

1. Department of Biochemical Sciences, Sapienza University of Rome - P. le Aldo Moro 5, 00185 Rome, Italy

2. Istituto di Biologia e Patologia Molecolari, Consiglio Nazionale delle Ricerche, 00185 Rome, Italy

3. Program Against Cancer Therapeutic Resistance (ProCURE), Metabolism and Cancer Group, Catalan Institute of Oncology, 17007 Girona, Catalonia, Spain

4. Molecular Oncology Group, Girona Biomedical Research Institute (IDIBGI), 17190 Girona, Spain

5. Department of Biology and Biotechnology ‘C. Darwin', Sapienza University of Rome, 00185 Rome, Italy

6. Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Dr. Aiguader 88, 08003 Barcelona, Spain

7. Universitat Pompeu Fabra (UPF), Department of Experimental and Health Sciences, 08003 Barcelona, Spain

8. Institucio Catalana de Recerca i Estudis Avançats (ICREA), Department of Life and Medical Sciences, 23 Passeig Lluıs Companys, 08010 Barcelona, Spain

Funder

Associazione Italiana per la Ricerca sul Cancro

Sapienza University of Rome

Istituto-Pasteur Italia-Fondazione Cenci Bolognetti

European Research Council

Spanish Ministry of Economy and Competitiveness

‘Fundació La Marató de TV3’

Ministerio de Ciencia e Innovación

Publisher

Oxford University Press (OUP)

Subject

Genetics

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