Characterization of Virus-specific Immune Response During Varicella Zoster Virus Encephalitis in a Young Adult-Reference-Cited by-同舟云学术

Characterization of Virus-specific Immune Response During Varicella Zoster Virus Encephalitis in a Young Adult

Published:2019-01-19 Issue:2 Volume:69 Page:348-351
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Sullivan Nicole L¹,Eberhardt Christiane S¹²,Wieland Andreas¹,Akondy Rama S¹,Yi Jumi³,McElroy Anita K³,Ahmed Rafi¹

Affiliation:

1. Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia

2. Department of Pediatrics and Pathology-Immunology, Center for Vaccinology and Neonatal Immunology, University Hospitals of Geneva and Faculty of Medicine, University of Geneva, Switzerland

3. Department of Pediatrics, Emory University School of Medicine and Children’s Healthcare of Atlanta, Georgia

Abstract

Abstract An immunocompetent adult received corticosteroids for chest pain, which later was clinically found to be herpes zoster (HZ). She developed severe disease and rapid viral dissemination that elicited an exceptionally strong varicella zoster virus–specific B-cell and CD8 T-cell response. Clinicians should consider atypical HZ presentation prior to corticosteroid administration.

Funder

National Institutes of Health

Fondation Eugenio Litta

Fond national suisse de la recherche scientifique

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Link

http://academic.oup.com/cid/article-pdf/69/2/348/33441504/ciy984.pdf

Reference15 articles.

1. Annual incidence rates of herpes zoster among an immunocompetent population in the United States;Johnson;BMC Infect Dis,2015