Atrophic autoimmune thyroiditis complicated with systemic lupus erythematosus

Author:

Wakatsuki Ryosuke1,Shimizu Masaki2ORCID,Shimbo Asami1,Adachi Eriko1,Kanamori Toru1,Yamazaki Susumu3,Udagawa Tomohiro1,Takasawa Kei1,Kashimada Kenichi1,Morio Tomohiro1,Mori Masaaki3

Affiliation:

1. Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University , Tokyo, Japan

2. Department of Child Health and Development, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University , Tokyo, Japan

3. Department of Lifetime Clinical Immunology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University , Tokyo, Japan

Abstract

ABSTRACT Atrophic autoimmune thyroiditis (AAT) is a type of autoimmune thyroiditis that causes hypothyroidism without thyroid enlargement. AAT is distinguished from Hashimoto’s disease (HD) by the absence of thyroid enlargement. AAT is rare in children and clinically characterised by severe primary hypothyroidism. Autoimmune thyroiditis, especially HD, is commonly complicated with systemic lupus erythematosus (SLE). Here, we reported the patient with AAT as the initial presentation of SLE complicated with generalised myxoedema, whose presentation was a diagnostic challenge. This patient illustrates the importance of the early recognition of an atypical presentation of SLE patients with autoimmune thyroiditis. It is possible that similar cases have existed in the past but have been overlooked as HD. A large-scale study is necessary to clarify the reality of AAT in SLE.

Funder

Dental University received unrestricted research

Clinical Immunology from AbbVie GK

Ayumi Pharmaceutical Corporation

Chugai Pharmaceutical Co., Ltd

CSL Behring K.K

Nippon Kayaku Co., Ltd

Pharmaceutical Co., Ltd

Towa Pharmaceutical Co., Ltd

UCB Japan Co. Ltd

Publisher

Oxford University Press (OUP)

Subject

Rheumatology

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3