Misidentification of Burkholderia pseudomallei as Acinetobacter species in northern Thailand-Reference-Cited by-同舟云学术

Misidentification of Burkholderia pseudomallei as Acinetobacter species in northern Thailand

Published:2018-10-05 Issue:1 Volume:113 Page:48-51
ISSN:0035-9203
Container-title:Transactions of The Royal Society of Tropical Medicine and Hygiene
language:en
Short-container-title:

Author:

Greer Rachel C¹²,Wangrangsimakul Tri¹²^ORCID,Amornchai Premjit¹,Wuthiekanun Vanaporn¹,Laongnualpanich Achara³,Dance David A B²⁴⁵,Limmathurotsakul Direk¹⁶^ORCID

Affiliation:

1. Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

2. Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK

3. Chiang Rai Prachanukroh Hospital, Chiang Rai, Thailand

4. Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Microbiology Laboratory, Mahosot Hospital, Vientiane Capital, Lao People’s Democratic Republic

5. Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK

6. Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

Abstract

Abstract Background Burkholderia pseudomallei is the causative agent of melioidosis, a disease endemic throughout the tropics. Methods A study of reported Acinetobacter spp. bacteraemia was performed at Chiang Rai provincial hospital from 2014 to 2015. Isolates were collected and tested for confirmation. Results A total of 419 putative Acinetobacter spp. isolates from 412 patients were re-identified and 5/419 (1.2%) were identified as B. pseudomallei. Four of the five patients with melioidosis died. An estimated 88/419 (21%) isolates were correctly identified as Acinetobacter spp. Conclusions Misidentification of Acinetobacter spp. as B. pseudomallei or other bacteria is not uncommon and programmes to address these shortfalls are urgently required.

Funder

Wellcome Trust

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,General Medicine,Parasitology

Link

http://academic.oup.com/trstmh/article-pdf/113/1/48/27330757/try108.pdf

Reference8 articles.

1. Melioidosis;Wiersinga;N Engl J Med,2012

2. Predicted global distribution of Burkholderia pseudomallei and burden of melioidosis;Limmathurotsakul;Nat Microbiol,2016

3. The epidemiology and clinical spectrum of melioidosis: 540 cases from the 20 year Darwin prospective study;Currie;PLoS Negl Trop Dis,2010