Persistence of <i>Trypanosoma cruzi</i> vector-borne transmission among school-age children in the Bolivian Chaco documented by 24-month longitudinal serosurveillance-Reference-Cited by-同舟云学术

Persistence of Trypanosoma cruzi vector-borne transmission among school-age children in the Bolivian Chaco documented by 24-month longitudinal serosurveillance

Published:2022-07-02 Issue:1 Volume:117 Page:58-60
ISSN:0035-9203
Container-title:Transactions of The Royal Society of Tropical Medicine and Hygiene
language:en
Short-container-title:

Author:

Spinicci Michele¹²^ORCID,Macchioni Fabio³,Gamboa Herlan⁴,Poma Veronica⁵,Villagrán Ana Liz⁶,Strohmeyer Marianne¹,Roselli Mimmo¹,Vargas Roberto⁷,Bartoloni Alessandro¹²,Gabrielli Simona⁸

Affiliation:

1. Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze , Firenze, Italy

2. SOD Malattie Infettive e Tropicali, Azienda Ospedaliero Universitaria Careggi , Firenze, Italy

3. Dipartimento di Scienze Veterinarie, Università di Pisa , Pisa, Italy

4. Facultad Integral del Chaco, Universidad Autónoma Gabriel René Moreno , Camiri, Bolivia

5. Escuela de Salud del Chaco Tekove Katu , Gutierrez, Bolivia

6. Hospital Básico de Villa Montes , Villa Montes, Bolivia

7. Servicio Departamental de Salud de Santa Cruz , Santa Cruz, Bolivia

8. Dipartimento di Sanità Pubblica e Malattie infettive, Università di Roma Sapienza , Roma, Italy

Abstract

Abstract Background Chagas disease represents a major public health concern in several Latin American countries, including Bolivia. Methods We present a longitudinal serosurvey for Trypanosoma cruzi antibodies among a cohort of 120 school-age children from rural communities in the Bolivian Chaco at three time points between 2017 and 2019. Serum samples extracted from dry blood spots collected on filter paper were tested for T. cruzi antibodies by enzyme-linked immunosorbent assay and rapid diagnostic test. Results T. cruzi antibodies were detected in 7/120 (5.8%), 8/120 (6.7%) and 11/120 (9.2%) samples in 2017, 2018 and 2019, respectively. An average incidence of 1.76 per 100 person-years was observed. Conclusions Our findings support the persistence of vector-borne T. cruzi transmission in this area, highlighting the need for strengthening multidisciplinary efforts against Chagas disease.

Funder

Regione Toscana

Ministry of Education, University and Research

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,General Medicine,Parasitology

Link

https://academic.oup.com/trstmh/article-pdf/117/1/58/48480150/trac065.pdf

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