Transfusion-transmissible dengue infections

Author:

Perera Lakshika12,De Zoysa Nandrani2,Jayarajah Umesh12ORCID,Senanayake Nilanthi3,De Zoysa Ishan12,Seneviratne Suranjith L12

Affiliation:

1. Department of Surgery, Faculty of Medicine, University of Colombo, Colombo 8, Sri Lanka

2. Dengue Research Group, Colombo, Sri Lanka

3. Department of Microbiology, Faculty of Medicine, University of Colombo, Colombo 8, Sri Lanka

Abstract

Abstract Dengue is an important global health problem and is endemic in many developing and developed countries. Transmission of dengue may occur in several ways and information on transfusion-transmitted dengue is limited. We conducted a literature search on transfusion-related dengue using the PubMed, Scopus, Embase and Google Scholar databases and have summarized the findings. A number of apparently healthy blood donors have been found to be infected with the dengue virus (DENV) and thus may transmit the virus onto recipients of this blood. It is not possible to identify and exclude such donors at the donor selection stage and thus reliable screening tests should be available in highly endemic areas to ensure a safe blood supply.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,General Medicine,Parasitology

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