First case of Zika virus infection during an outbreak of chikungunya in a rural region of Maharashtra state, India

Author:

Gurav Yogesh K1ORCID,Alagarasu Kalichamy1,Yadav Pragya D1,Sapkal Gajanan1ORCID,Gokhale Mangesh1,Parashar Deepti1,Jadhav Ujwala2,Bote Minal1,Kakade Mahadeo1,Nyayanit Dimpal1,Kumar Abhinendra1,Deshpande Gururaj Rao1,Cherian Sarah1,Awate Pradip S3,Abraham Priya1

Affiliation:

1. ICMR-National Institute of Virology , Pune, Maharashtra, India

2. Taluka Health Officer, Purandar , District Pune, Maharashtra, India

3. State Surveillance Officer, Integrated Diseases Surveillance Programme , Maharashtra, India

Abstract

Abstract Background In July 2021, an outbreak of chikungunya virus (CHIKV) was reported in a rural region of Maharashtra state, India. Methods Serum samples of symptomatic cases (n=33) were screened for dengue virus (DENV), CHIKV and Zika virus (ZIKV) by molecular and serological assays. Results The first case of ZIKV infection from Maharashtra was detected and confirmed by molecular and serological assays. Complete genome sequencing revealed that the ZIKV sequence belongs to the Asian genotype and had a closer homology with pre-epidemic strains present before 2007. Conclusions ZIKV surveillance needs to be strengthened in the regions experiencing dengue and chikungunya outbreaks.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,General Medicine,Parasitology

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