Lessons from the field: compound-specific management in acute pesticide poisoning

Author:

Verma Vasundhara R1,Lamb Thomas1ORCID,Sattar Md Abdus2,Ghose Aniruddha2,Eddleston Michael134

Affiliation:

1. Pharmacology, Toxicology and Therapeutics, University/BHF Centre for Cardiovascular Science, University of Edinburgh , UK

2. Department of Medicine, Chittagong Medical College and Hospital , Chattogram , Bangladesh

3. South Asian Clinical Toxicology Research Collaboration, University of Peradeniya , Peradeniya , Sri Lanka

4. Centre for Pesticide Suicide Prevention, University of Edinburgh , UK

Abstract

Abstract Pesticide poisoning is a common medical emergency in the rural tropics, with significant associated mortality. Pesticide poisoning is an umbrella term that encompasses a wide variety of substances with differing clinical toxidromes and outcomes. Despite this, confirmation of the specific compound ingested is rarely performed. In this Lessons from the Field, we argue that pesticide-specific management is integral to optimise management. Using data from a quality improvement project in Chittagong, Bangladesh, we demonstrate that identifying the specific compound is possible in most patients through careful history taking and examination of the pesticide bottle. Identification of the specific compound is essential for anticipating and reducing complications, administering appropriate and timely management and reducing the length of hospital stay and cost of unnecessary medical intervention.

Funder

Centre for Pesticide Suicide Prevention

Open Philanthropy

Publisher

Oxford University Press (OUP)

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